| Name | phosphoinositide 3 kinase (protein family or complex) |
|---|---|
| Synonyms | phosphoinositide 3 kinase; phosphoinositide 3 kinases |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19077054 | Noh MY, Koh SH, Kim Y, Kim HY, Cho GW, Kim SH: Neuroprotective effects of through inhibition of GSK-3 activity in amyloid-beta-induced neuronal cell death. J Neurochem. 2009 Mar;108(5):1116-25. Epub 2009 Jan 23. The neuroprotective effects of were blocked by LY294002 (10 microM), a phosphoinositide 3 kinase inhibitor, but only partially by mecamylamine (10 microM), a blocker of nicotinic acetylcholine receptors. |
2(0,0,0,2) | Details |
| 19077124 | Welsby PJ, Rowan MJ, Anwyl R: Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus. Eur J Neurosci. 2009 Jan;29(1):65-75. Epub 2008 Dec 11. Moreover, activation of phosphoinositide 3-kinase was involved in the acute nicotinic enhancement of LTP to a much lesser extent than in control LTP. Chronic nicotine enhancement of LTP was found to be dependent on PKA, ERK and Src kinases. |
1(0,0,0,1) | Details |
| 19499400 | Junhui Z, Xiaojing H, Binquan Z, Xudong X, Junzhu C, Guosheng F: Nicotine-reduced endothelial progenitor cell senescence through augmentation of telomerase activity via the PI3K/Akt pathway. Cytotherapy. 2009;11(4):485-91. Nicotine significantly increased telomerase activity and phosphorylation of Akt, a downstream effector of phosphoinositide 3-kinase (PI3K). |
81(1,1,1,1) | Details |
| 19729077 | Jeong GS, Lee SH, Jeong SN, Kim YC, Kim EC: Anti-inflammatory effects of on nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via heme oxygenase-1. Int Immunopharmacol. 2009 Nov;9(12):1374-80. Epub 2009 Sep 1. Treatment with inhibitors of the phosphoinositide 3-kinase, MAPKs, p38, and JNK, as well as a protein kinase C inhibitor, blocked the anti-inflammatory effects of in nicotine- and LPS-treated cells. |
31(0,1,1,1) | Details |