| Name | osteopontin |
|---|---|
| Synonyms | BNSP; Spp1; BSPI; Bone sialoprotein; Bone sialoprotein 1; ETA 1; ETA1; Early T lymphocyte activation 1… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19054295 | Nakayama Y, Mezawa M, Araki S, Sasaki Y, Wang S, Han J, Li X, Takai H, Ogata Y: Nicotine suppresses bone sialoprotein gene expression. J Periodontal Res. 2009 Oct;44(5):657-63. Epub 2008 Nov 11. |
82(1,1,1,2) | Details |
| 19358273 | Chipitsyna G, Gong Q, Anandanadesan R, Alnajar A, Batra SK, Wittel UA, Cullen DM, Akhter MP, Denhardt DT, Yeo CJ, Arafat HA: Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells. Int J Cancer. 2009 Jul 15;125(2):276-85. |
7(0,0,1,2) | Details |
| 19656028 | Lee HJ, Pi SH, Kim Y, Kim HS, Kim SJ, Kim YS, Lee SK, Kim EC: Effects of nicotine on antioxidant defense enzymes and RANKL expression in human periodontal ligament cells. J Periodontol. 2009 Aug;80(8):1281-8. RESULTS: Nicotine treatment concomitantly downregulated the expression of OPG and osteoblastic differentiation markers, such as alkaline phosphatase, osteocalcin, and osteopontin, and upregulated the expression of RANKL. |
6(0,0,1,1) | Details |
| 19359522 | Prasse A, Stahl M, Schulz G, Kayser G, Wang L, Ask K, Yalcintepe J, Kirschbaum A, Bargagli E, Zissel G, Kolb M, Muller-Quernheim J, Weiss JM, Renkl AC: Essential role of osteopontin in smoking-related interstitial lung diseases. Am J Pathol. 2009 May;174(5):1683-91. Epub 2009 Apr 9. Nicotine stimulation increased production of both OPN and granulocyte-macrophage colony stimulating factor by alveolar macrophages from smokers. |
2(0,0,0,2) | Details |
| 19628079 | Sullivan J, Blair L, Alnajar A, Aziz T, Ng CY, Chipitsyna G, Gong Q, Witkiewicz A, Weber GF, Denhardt DT, Yeo CJ, Arafat HA: Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma. Surgery. 2009 Aug;146(2):232-40. We demonstrated recently that nicotine, a major risk factor in pancreatic ductal adenocarcinoma (PDA), increases OPN expression in PDA cells. |
2(0,0,0,2) | Details |
| 19546357 | Zhou YB, Jin SJ, Cai Y, Teng X, Chen L, Tang CS, Qi YF: Lanthanum inhibits vascular calcification induced by plus nicotine in rats. Exp Biol Med. 2009 Aug;234(8):908-17. Epub 2009 Jun 22. As compared with control rats, rats with calcification showed widespread calcified nodules and irregular elastic fibers in calcified aorta on von Kossa staining and increased aortic and contents, alkaline phosphatase (ALP) activity and bone-related protein expressions for osteopontin (OPN) and type III dependent cotransporter Pit-1 (Pit-1). |
1(0,0,0,1) | Details |
| 19481023 | Khanna AK, Xu J, Baquet C, Mehra MR: Adverse effects of nicotine and immunosuppression on proximal tubular epithelial cell viability, tissue repair and oxidative stress gene expression. J Heart Lung Transplant. 2009 Jun;28(6):612-20. Epub 2009 May 5. Compared with control, treatment of PTE cells with N increased mRNA expression of transforming growth factor-beta (TGF-beta; 10-fold), connective tissue growth factor (CTGF; 25-fold), osteopontin (OPN; 10-fold) and oxidase components (p22 (phox), NOX-1 and Rac-1 at 18-, 16- and 12-fold, respectively). |
1(0,0,0,1) | Details |