Protein Information

Name tissue type plasminogen activator
Synonyms Alteplase; Neonatal thrombolytic agent alpha form; PLAT; PLAT protein; Reteplase; T PA; TPA; TPA protein…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19098386 Nagai T, Nabeshima T, Yamada K: Basic and translational research on proteinase-activated receptors: regulation of nicotine reward by the tissue plasminogen activator (tPA) - plasmin system via proteinase-activated receptor 1. J Pharmacol Sci. 2008 Dec;108(4):408-14.
43(0,1,3,3) Details
19602125 Ho YC, Yang SF, Huang FM, Chang YC: Up-regulation of osteolytic mediators in human osteosarcoma cells stimulated with nicotine. J Periodontal Res. 2009 Dec;44(6):760-6. Epub 2009 Jul 8.

The aim of this study was to investigate the expression of interleukin-1, interleukin-8, receptor activator of nuclear factor-kappaB ligand (RANKL), gelatinases and tissue-type plasminogen activator in U2OS cells (from the human osteosarcoma cell line) stimulated with nicotine.
39(0,1,2,4) Details