Protein Information

Name albumin
Synonyms ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19140513 Nezhinskaia GI, Vladykin AL, Sapronov NS: [Effects of cholinergic drugs and blood plasma proteins on the development of Arthus reaction]. Eksp Klin Farmakol. 2008 Nov-Dec;71(6):31-3.

The administration of acetylcholine, nicotine, and combinations of muscarinic antagonists with neostigmine, as well as gamma globulin and albumin resulted in the later onset of Arthus reaction.
112(1,2,2,2) Details
19593403 Rosas-Ballina M, Goldstein RS, Gallowitsch-Puerta M, Yang L, Valdes-Ferrer SI, Patel NB, Chavan S, Al-Abed Y, Yang H, Tracey KJ: The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE. Mol Med. 2009 Jul-Aug;15(7-8):195-202. Epub 2009 Apr 27.

The suppressive effect of GTS-21 was more potent than nicotine in whole blood and monocytes.
Furthermore, GTS-21 attenuated TNF production in monocytes stimulated with peptidoglycan, polyinosinic-polycytidylic acid, CpG, HMGB1 (high-mobility group box 1 protein), and advanced glycation end product-modified albumin.
1(0,0,0,1) Details