| Name | Pit 1 |
|---|---|
| Synonyms | GLVR 1; PIT1; Pit 1; GLVR1; Gibbon ape leukemia virus receptor 1; Leukemia virus receptor 1 homolog; Phosphate transporter 1; SLC20A1… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19546357 | Zhou YB, Jin SJ, Cai Y, Teng X, Chen L, Tang CS, Qi YF: Lanthanum inhibits vascular calcification induced by plus nicotine in rats. Exp Biol Med. 2009 Aug;234(8):908-17. Epub 2009 Jun 22. Lanthanum at 750 mg/kg/day was more effective than 375 mg/kg/day in lessening vascular calcification by significantly reducing plasma level, x product and ALP activity, by 30.3%, 28.6%, and 68.6%, respectively; reducing aortic and contents and ALP activity, by 48%, 53.1%, and 63.5% (all P < 0.01), respectively; reducing aortic mRNA level of OPN and Pit-1, by 55.8% (P < 0.01) and 38.8% (P < 0.05) and protein level of OPN and Pit-1, by 37.2% and 27.2% (both P < 0.01), respectively; and increasing carboxylated matrix Gla-protein (MGP) protein expression by 33.7% (P < 0.05), as compared with rats treated with and nicotine alone. |
32(0,1,1,2) | Details |
| 19766150 | Liu Y, Zhou YB, Zhang GG, Cai Y, Duan XH, Teng X, Song JQ, Shi Y, Tang CS, Yin XH, Qi YF: Cortistatin attenuates vascular calcification in rats. Regul Pept. 2010 Jan 8;159(1-3):35-43. Epub . In this study, we investigated in rats whether CST inhibits vascular calcification induced by and nicotine treatment in vivo and calcification of cultured rat vascular smooth muscular cells (VSMCs) induced by beta-glycerophosphate in vitro and the underlying mechanism. CST also significantly decreased ALP activity and calcium deposition, alleviated pathological injury and down-regulated the mRNA expression of type III -dependent co-transporter-1 (Pit-1) in aortic tissues. |
2(0,0,0,2) | Details |