| Name | glucocorticoid receptor |
|---|---|
| Synonyms | GCCR; GCR; GR; GRL; Glucocorticoid receptor; NR3C1; Glucocorticoid receptors |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19476543 | Radcliffe PM, Sterling CR, Tank AW: Induction of tyrosine hydroxylase mRNA by nicotine in rat midbrain is inhibited by mifepristone. J Neurochem. 2009 Jun;109(5):1272-84. Epub 2009 Mar 23. We tested the hypothesis that the effect of nicotine on midbrain TH mRNA is mediated by the glucocorticoid receptor. |
144(1,3,3,4) | Details |
| 20153739 | Hunter RG, Bloss EB, McCarthy KJ, McEwen BS: Regulation of the nicotinic receptor alpha7 subunit by chronic stress and corticosteroids. Brain Res. 2010 Feb 11. The alpha7 subunit of the nicotinic acetylcholine receptor (NAchRalpha7) is one of the principal brain receptors for nicotine and is thought to be a mediator of nicotine's pro-cognitive effects. We examined the effects of chronic (21day) restraint stress (CRS) and adrenalectomy with hormone replacement with the selective mineralocorticoid receptor (MR) agonist the selective glucocorticoid receptor (GR) agonist RU28,362 or for 7days, on the hippocampal expression of NAchRalpha7 mRNA and protein, as measured by (125) I alpha-Bungarotoxin autoradiography. |
1(0,0,0,1) | Details |
| 19702528 | Di YM, Chow VD, Yang LP, Zhou SF: Structure, Function, Regulation and Polymorphism of Human Cytochrome P450 2A6. Curr Drug Metab. 2009 Sep 1. The CYP2A6 protein has 494 amino acids and is an important hepatic Phase I enzyme that metabolizes approximately 3% of therapeutic drugs (n > 30; e.g. pilocarpine, tegafur, fadrozole, ifosfamide, cyclophosphamide, nicotine, tamoxifen, promazine, propofol, and cisapride), environmental toxicants (e.g. gasoline additives), and many procarcinogens such as nitrosamines and aflatoxin B (1). |
0(0,0,0,0) | Details |