Protein Information

Name sulfatase
Synonyms ARS; RGS 2; RGS2; RIEG 2; RIEG2; ARS; Arylsulfatase C; nitrocatechol sulfatase…

Compound Information

Name lindane
CAS (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane

Reference List

PubMed Abstract RScore(About this table)
16818664 Corcelle E, Nebout M, Bekri S, Gauthier N, Hofman P, Poujeol P, Fenichel P, Mograbi B: Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity. Cancer Res. 2006 Jul 1;66(13):6861-70.

Such Lindane-induced vacuolation results from significant delay in autophagy degradation, in relation with a decline of the lysosomal activity of aryl sulfatase A.
81(1,1,1,1) Details