| Name | sulfonylurea receptor |
|---|---|
| Synonyms | ABC36; PHHI; MRP8; HI; ABCC 8; ABCC8; ATP binding cassette transporter sub family C member 8; HHF 1… |
| Name | rotenone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16837559 | Wu J, Hu J, Chen YP, Takeo T, Suga S, Dechon J, Liu Q, Yang KC, St John PA, Hu G, Wang H, Wakui M: Iptakalim modulates ATP-sensitive K (+) channels in neurons from rat substantia nigra pars compacta. J Pharmacol Exp Ther. 2006 Oct;319(1):155-64. Epub 2006 Jul 12. In identified DA neurons acutely dissociated from rat substantia nigra pars compacta (SNc), both the mitochondrial metabolic inhibitor rotenone and the sulfonylurea receptor subtype (SUR) 1-selective K (ATP) channel opener (KCO) diazoxide induced neuronal hyperpolarization and abolished action potential firing, but the SUR2B-selective KCO cromakalim exerted little effect, suggesting that functional K (ATP) channels in rat SNc DA neurons are mainly composed of SUR1. |
33(0,1,1,3) | Details |
| 10022826 | Liss B, Bruns R, Roeper J: Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons. EMBO J. 1999 Feb 15;18(4):833-46. |
4(0,0,0,4) | Details |
| 12603842 | Tai KK, McCrossan ZA, Abbott GW: Activation of mitochondrial ATP-sensitive channels increases cell viability against rotenone-induced cell death. J Neurochem. 2003 Mar;84(5):1193-200. Using specific antibodies against SUR1 and Kir6.1, we detected immunoreactive proteins of apparent molecular masses 155 and 50 kDa, corresponding to those previously reported for SUR1 and Kir6.1, respectively, in the mitochondria-enriched fraction of PC12 cells. |
1(0,0,0,1) | Details |