Protein Information

Name Mannose Binding Lectin
Synonyms COLEC 1; COLEC1; HSMBPC; Lectin mannose binding soluble 2; MBL; MBL 2; MBL2; MBP…

Compound Information

Name EPN
CAS

Reference List

PubMed Abstract RScore(About this table)
16542855 Nikolakopoulou K, Zarkadis IK: Molecular cloning and characterisation of two homologues of Mannose-Binding Lectin in rainbow trout. Fish Shellfish Immunol. 2006 Sep;21(3):305-14. Epub 2006 Mar 15.

3(0,0,0,3) Details
17169576 Gourdine JP, Smith-Ravin EJ: Analysis of a cDNA-derived sequence of a novel mannose-binding lectin, codakine, from the tropical clam Codakia orbicularis. Fish Shellfish Immunol. 2007 May;22(5):498-509. Epub 2006 Jul 10.

2(0,0,0,2) Details
11003389 Vitved L, Holmskov U, Koch C, Teisner B, Hansen S, Salomonsen J, Skjodt K: The homologue of mannose-binding lectin in the carp family Cyprinidae is expressed at high level in spleen, and the deduced primary structure predicts affinity for galactose. Immunogenetics. 2000 Sep;51(11):955-64.

2(0,0,0,2) Details
17890508 Bulgakov AA, Eliseikina MG, Petrova IY, Nazarenko EL, Kovalchuk SN, Kozhemyako VB, Rasskazov VA: Molecular and biological characterization of a mannan-binding lectin from the holothurian Apostichopus japonicus. Glycobiology. 2007 Dec;17(12):1284-98. Epub 2007 Sep 21.


Taking into consideration such MBL-AJ peculiarities as its carbohydrate specificity, the presence of a conserved region forming the mannose-binding site, common antigenic determinants with human MBL, and participation in defense reactions, it is possible that MBL-AJ belongs to the family of evolutionary conserved mannan-binding proteins.
1(0,0,0,1) Details