Protein Information

Name MEKK
Synonyms MAP3K1; MAPK/ERK kinase kinase 1; MAPKKK 1; MAPKKK1; MEK kinase 1; MEKK; MEKK 1; MEKK1…

Compound Information

Name heptachlor
CAS

Reference List

PubMed Abstract RScore(About this table)
9704902 Chuang LF, Chuang RY: Heptachlor and the mitogen-activated protein kinase module in human lymphocytes. Toxicology. 1998 Jun 26;128(1):17-23.

Addition of heptachlor to human CEM x174 lymphocytic cells reduced the cellular levels of MAP kinase (MAPK, mitogen-activated protein kinase) cascade proteins, including ERK1 (a 44-kDa MAPK), ERK2 (a 42-kDa MAPK), a 85-kDa and a 54-kDa MAP kinase, MEK1 (a 45-kDa ERK kinase) and MEKK (a 78-kDa MEK kinase).
31(0,1,1,1) Details