| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | azamethiphos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17266995 | Canty MN, Hagger JA, Moore RT, Cooper L, Galloway TS: Sublethal impact of short term exposure to the organophosphate pesticide azamethiphos in the marine mollusc Mytilus edulis. Mar Pollut Bull. 2007 Apr;54(4):396-402. Epub 2007 Jan 30. The distribution and sensitivity of M. edulis acetylcholinesterase to inhibition by azamethiphos was first determined, yielding IC (50) values of 0.736 and 1.30 mg l (-1) for gill and haemolymph, respectively. |
163(2,2,2,3) | Details |
| 16718740 | Kristensen M, Huang J, Qiao CL, Jespersen JB: Variation of Musca domestica L. acetylcholinesterase in Danish housefly populations. Pest Manag Sci. 2006 Aug;62(8):738-45. Cluster analysis was performed and > 2000 houseflies were assigned to one of three phenotypes based on total acetylcholinesterase activity as well as inhibition by azamethiphos, methomyl or omethoate. |
120(1,2,3,5) | Details |
| 18484351 | Tarhoni MH, Lister T, Ray DE, Carter WG: Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides. Biomarkers. 2008 Jun;13(4):343-63. At pesticide exposures producing approximately 30% inhibition of AChE, rat plasma albumin binding in vitro by azamethiphos (oxon), chlorfenvinphos (oxon), chlorpyrifos-oxon, diazinon-oxon and malaoxon was reduced from controls by 9+/-1%, 67+/-2%, 56+/-2%, 54+/-2% and 8+/-1%, respectively. |
82(1,1,1,2) | Details |
| 15578596 | Fallang A, Ramsay JM, Sevatdal S, Burka JF, Jewess P, Hammell KL, Horsberg TE: Evidence for occurrence of an organophosphate-resistant type of acetylcholinesterase in strains of sea lice (Lepeophtheirus salmonis Kroyer). Pest Manag Sci. 2004 Dec;60(12):1163-70. A bimolecular rate assay demonstrated the presence of two AChE enzymes with different sensitivities towards azamethiphos, one that was rapidly inactivated and one that was very slowly inactivated. |
34(0,1,1,4) | Details |
| 16931084 | Romani R, Corsi I, Bonacci S, Focardi S, De Medio GE, De Santis A, Incarnato F, Giovannini E, Rosi G: Organophosphate-resistant forms of acetylcholinesterases in two scallops--the Antarctic Adamussium colbecki and the Mediterranean Pecten jacobaeus. Comp Biochem Physiol B Biochem Mol Biol. 2006 Oct;145(2):188-96. Epub 2006 Jul 20. Differently, the adductor muscle amphiphilic forms are resistant to eserine and organophosphate diisopropylfluorophosphate, but sensitive to organophoshate azamethiphos. |
9(0,0,0,9) | Details |
| 14643697 | Intorre L, Soldani G, Cognetti-Varriale AM, Monni G, Meucci V, Pretti C: Safety of azamethiphos in eel, seabass and trout. Pharmacol Res. 2004 Feb;49(2):171-6. Compared to controls, brain acetylcholinesterase (AChE) was inhibited up to 44, 56 and 62% in eels, seabass and trout, respectively, with the inhibition being significant for up to 4 days in eels and seabass and 7 days in trout. |
3(0,0,0,3) | Details |
| 1637204 | Fossi MC, Leonzio C, Massi A, Lari L, Casini S: Serum esterase inhibition in birds: a nondestructive biomarker to assess organophosphorus and contamination. Arch Environ Contam Toxicol. 1992 Jul;23(1):99-104. With the aim of proposing a nondestructive biomarker for monitoring the toxicological risk to birds of exposure to the organophosphorus insecticide azamethiphos and the insecticide methomyl, laboratory studies were performed on serum "B" esterases in Japanese quail (Coturnix coturnix japonica). Serum BChE and brain acetylcholinesterase (AChE) were strongly inhibited after treatment with both insecticides. |
2(0,0,0,2) | Details |
| 14580806 | Brown M, Davies IM, Moffat CF, Redshaw J, Craft JA: Characterisation of esterases and their tissue and subcellular distribution in mussel (Mytilus edulis). Mar Environ Res. 2004 Apr;57(3):155-69. Acetylcholinesterase in mussel is potentially a useful biomarker of exposure to organophosphates (OP) in the marine environment. Inhibition of cholinesterase activity by azamethiphos in gill 'microsomal' fraction gave an IC50 of approximately 100 microM and showed both time and concentration dependence. |
2(0,0,0,2) | Details |
| 2904862 | Price NR: Insecticide-insensitive acetylcholinesterase from a laboratory selected and a field strain of housefly (Musca domestica) (L.). Comp Biochem Physiol C. 1988;90(1):221-4. The enzyme from resistant insects was also more tolerant to malaoxon, dichlorvos and bomyl but not to azamethiphos. 3. |
2(0,0,0,2) | Details |
| 18177688 | Stefano B, Ilaria C, Silvano F: Cholinesterase activities in the scallop Pecten jacobaeus: characterization and effects of exposure to aquatic contaminants. Sci Total Environ. 2008 Mar 15;392(1):99-109. Epub 2008 Jan 3. The main aims of the present study were: 1) to characterize the biochemical properties of ChEs in tissues of the bivalve Pecten jacobaeus, using different specific substrates and selective inhibitors; 2) to measure sensitivity of ChE activities to in vitro exposure to the OPs azamethiphos and DFP and to the heavy metals cadmium and zinc. Responses to specific inhibitors have suggested that ChEs in adductor muscle share many characteristics with vertebrate acetylcholinesterase. |
1(0,0,0,1) | Details |
| 11142314 | Kristensen M, Knorr M, Spencer AG, Jespersen JB: Selection and reversion of azamethipos-resistance in a field population of the housefly Musca domestica (Diptera: Muscidae), and the underlying biochemical mechanisms. J Econ Entomol. 2000 Dec;93(6):1788-95. The organophosphorus insecticide, azamethiphos, is widely used throughout the world to control the housefly, Musca domestica (L.). Through the analysis of a field derived laboratory strain, we have implicated oxidative and hydrolytic mechanisms together with altered acetylcholinesterase in this resistance. |
1(0,0,0,1) | Details |
| 1517504 | Saito K, Motoyama N, Dauterman WC: Effect of synergists on the oral and topical toxicity of azamethiphos to organophosphate-resistant houseflies (Diptera: Muscidae). J Econ Entomol. 1992 Aug;85(4):1041-5. The hydrolytic enzymes are more important, but other factors including reduced cuticular penetration and insensitive acetylcholinesterase may be involved.(ABSTRACT TRUNCATED AT 250 WORDS) |
1(0,0,0,1) | Details |
| 1787217 | Saito K, Motoyama N, Dauterman WC: Studies on the resistance to various insecticides of a house fly strain (Diptera: Muscidae) selected with azamethiphos. J Econ Entomol. 1991 Dec;84(6):1635-7. We conclude that the main mechanisms responsible for resistance are presumed to be factors other than acetylcholinesterase sensitivity and nerve sensitivity due to knockdown resistance. |
1(0,0,0,1) | Details |
| 17324630 | Corsi I, Pastore AM, Lodde A, Palmerini E, Castagnolo L, Focardi S: Potential role of cholinesterases in the invasive capacity of the freshwater bivalve, Anodonta woodiana (Bivalvia: Unionacea): a comparative study with the indigenous species of the genus, Anodonta sp. Comp Biochem Physiol C Toxicol Pharmacol. 2007 Apr;145(3):413-9. Epub 2007 Feb 1. Similar IC (50) of 10 (-5)-10 (-6) M were observed for DFP and azamethiphos in both species. The hypotheses of other authors that acetylcholinesterase (AChE) is involved in the control of many essential functions, such as frontal ciliary activity of gill epithelium, temperature resistance, ciliary activity for transport of suspended particulate, valve opening and embryo development, suggest that the high catalytic efficiency of the invasive species may endow it with a competitive advantage over the endemic species. |
1(0,0,0,1) | Details |
| 16475215 | Fallang A, Larsen S, Horsberg TE: Upper susceptibility threshold limits with confidence intervals: a method to identify normal and abnormal population values for laboratory toxicological parameters, based on acetylcholinesterase activities in sea lice. Pest Manag Sci. 2006 Mar;62(3):208-13. |
1(0,0,0,1) | Details |
| 17615116 | Carter WG, Tarhoni M, Rathbone AJ, Ray DE: Differential protein adduction by seven organophosphorus pesticides in both brain and thymus. Hum Exp Toxicol. 2007 Apr;26(4):347-53. We found significant adduction of partially characterized protein targets in both rat brain and thymus by azamethiphos, chlorfenvinphos, chlorpyrifos-oxon, diazinon-oxon, dichlorvos and malaoxon, in vitro and pirimiphos-methyl in vivo. |
0(0,0,0,0) | Details |