Protein Information

Name glutathione S transferases
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name spiromesifen
CAS 2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate

Reference List

PubMed Abstract RScore(About this table)
19170251 Van Pottelberge S, Van Leeuwen T, Khajehali J, Tirry L: Genetic and biochemical analysis of a laboratory-selected spirodiclofen-resistant strain of Tetranychus urticae Koch (Acari: Tetranychidae). Pest Manag Sci. 2009 Apr;65(4):358-66.

No cross-resistance was found against other established acaricides, except for spiromesifen.
Based on synergist experiments and enzyme assays, it appeared that especially P450 monooxygenases, but also esterases and glutathione-S-transferases, could be involved in the metabolic detoxification of spirodiclofen.
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