Protein Information

Name ACS2
Synonyms ACS 2; LACS2; Long chain acyl CoA synthetase 2; ACS2; Long chain acyl CoA synthetase 5; ACSL 6; ACSL6; Acyl CoA synthetase 2…

Compound Information

Name 1-methylcyclopropene
CAS 1-methylcyclopropene

Reference List

PubMed Abstract RScore(About this table)
16881689 Zheng QL, Nakatsuka A, Itamura H: Involvement of negative feedback regulation in wound-induced ethylene synthesis in 'Saijo' persimmon. J Agric Food Chem. 2006 Aug 9;54(16):5875-9.

We found that wound-induced ethylene biosynthesis is subjected to negative feedback regulation in mature 'Saijo' persimmon fruit since ethylene production was enhanced by 1-methylcyclopropene (1-MCP) (an inhibitor of ethylene perception) pretreatment, which was approximately 1.8 fold of that in control tissues (without 1-MCP pretreatment).
Wound-induced 1-aminocyclopropane-1-carboxylate (ACC) synthase activity and DK-ACS2 gene expression were substantially increased by 1-MCP pretreatment after 12 h, which resulted in much higher ACC content in 1-MCP pretreated tissues than that in a control after 24 h.
2(0,0,0,2) Details
9847103 Nakatsuka A, Murachi S, Okunishi H, Shiomi S, Nakano R, Kubo Y, Inaba A: Differential expression and internal feedback regulation of 1-aminocyclopropane-1-carboxylate synthase, 1-aminocyclopropane-1-carboxylate oxidase, and ethylene receptor genes in tomato fruit during development and ripening. Plant Physiol. 1998 Dec;118(4):1295-305.

The abundance of LE-ACS2, LE-ACS4, and NR mRNAs increased in the ripening fruit concomitant with a burst in ethylene production.
These increases in mRNAs with ripening were prevented to a large extent by treatment with 1-methylcyclopropene (MCP), an ethylene action inhibitor.
2(0,0,0,2) Details
12529535 Nakano R, Ogura E, Kubo Y, Inaba A: Ethylene biosynthesis in detached young persimmon fruit is initiated in calyx and modulated by water loss from the fruit. Plant Physiol. 2003 Jan;131(1):276-86.

In all tissues except the calyx, treatment with 1-methylcyclopropene, an inhibitor of ethylene action, suppressed ethylene production and ethylene biosynthesis-related gene expression.
Furthermore, the alleviation of water loss from the fruit significantly delayed the onset of ethylene production and the expression of DK-ACS2 in the calyx.
2(0,0,0,2) Details
16844735 Ma N, Tan H, Liu X, Xue J, Li Y, Gao J: Transcriptional regulation of ethylene receptor and CTR genes involved in ethylene-induced flower opening in cut rose (Rosa hybrida) cv. J Exp Bot. 2006;57(11):2763-73. Epub 2006 Jul 14.

However, although ethylene hastened the process of flower opening, 1-MCP (1-methylcyclopropene), an ethylene action inhibitor, impeded it.
Of the four ethylene biosynthetic genes tested, Rh-ACS1 and Rh-ACS2 were undetectable; Rh-ACS3 and Rh-ACO1 expression was enhanced by ethylene slightly and greatly, respectively.
1(0,0,0,1) Details
15983011 Marcos JF, Gonzalez-Candelas L, Zacarias L: Involvement of ethylene biosynthesis and perception in the susceptibility of citrus fruits to Penicillium digitatum infection and the accumulation of defence-related mRNAs. J Exp Bot. 2005 Aug;56(418):2183-93. Epub 2005 Jun 27.


Blocking ethylene perception by 1-MCP resulted in an increased ethylene production and ACS2 expression during infection and mechanical wounding, suggesting that this gene is negatively regulated by ethylene.
1(0,0,0,1) Details
16889975 Owino WO, Manabe Y, Mathooko FM, Kubo Y, Inaba A: Regulatory mechanisms of ethylene biosynthesis in response to various stimuli during maturation and ripening in fig fruit (Ficus carica L.). Plant Physiol Biochem. 2006 May-Jun;44(5-6):335-42. Epub 2006 Jul 7.

The ethylene production in response to olive oil, auxin, and propylene treatments and during ripening were all induced by 1-methylcyclopropene (1-MCP) and inhibited by propylene indicating a negative feedback regulation mechanism.
Three 1-aminocyclopropane-1-carboxylic acid (ACC) synthase genes (Fc-ACS1, Fc-ACS2 and Fc-ACS3) and one ACC oxidase gene (Fc-ACO1) were isolated and their expression patterns in response to either oil, propylene or auxin treatment in figs determined.
1(0,0,0,1) Details