Protein Information

Name 1 aminocyclopropane 1 carboxylate synthase
Synonyms 1 aminocyclopropane 1 carboxylate synthase; ACS; ACC synthase; PHACS; ACC synthases

Compound Information

Name 1-methylcyclopropene
CAS 1-methylcyclopropene

Reference List

PubMed Abstract RScore(About this table)
15349780 Woltering EJ, Balk PA, Nijenhuis-Devries MA, Faivre M, Ruys G, Somhorst D, Philosoph-Hadas S, Friedman H: An auxin-responsive 1-aminocyclopropane-1-carboxylate synthase is responsible for differential ethylene production in gravistimulated Antirrhinum majus L. flower stems. Planta. 2005 Jan;220(3):403-13. Epub 2004 Sep 2.

IAA-induced growth of vertical stem sections and bending of gravistimulated flowering stems were little affected by ethylene or 1-methylcyclopropene treatments, indicating that the differential ethylene production plays no pivotal role in the kinetics of gravitropic bending.
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19587104 Wang A, Yamakake J, Kudo H, Wakasa Y, Hatsuyama Y, Igarashi M, Kasai A, Li T, Harada T: Null mutation of the MdACS3 gene, coding for a ripening-specific 1-aminocyclopropane-1-carboxylate synthase, leads to long shelf life in apple fruit. Plant Physiol. 2009 Sep;151(1):391-9. Epub 2009 Jul 8.

Because MdACS3 expression continues in ripening fruit treated with 1-methylcyclopropene, its transcription appears to be regulated by a negative feedback mechanism.
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16881689 Zheng QL, Nakatsuka A, Itamura H: Involvement of negative feedback regulation in wound-induced ethylene synthesis in 'Saijo' persimmon. J Agric Food Chem. 2006 Aug 9;54(16):5875-9.

We found that wound-induced ethylene biosynthesis is subjected to negative feedback regulation in mature 'Saijo' persimmon fruit since ethylene production was enhanced by 1-methylcyclopropene (1-MCP) (an inhibitor of ethylene perception) pretreatment, which was approximately 1.8 fold of that in control tissues (without 1-MCP pretreatment).
Wound-induced 1-aminocyclopropane-1-carboxylate (ACC) synthase activity and DK-ACS2 gene expression were substantially increased by 1-MCP pretreatment after 12 h, which resulted in much higher ACC content in 1-MCP pretreated tissues than that in a control after 24 h.
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17185740 Inaba A, Liu X, Yokotani N, Yamane M, Lu WJ, Nakano R, Kubo Y: Differential feedback regulation of ethylene biosynthesis in pulp and peel tissues of banana fruit. J Exp Bot. 2007;58(5):1047-57. Epub 2006 Dec 21.

Grand Nain] fruit was investigated in an attempt to clarify the opposite effect of 1-methylcyclopropene (1-MCP), an ethylene action inhibitor, before and after the onset of ripening. 1-MCP pre-treatment completely prevented the ripening-induced effect of propylene in pre-climacteric banana fruit, whereas treatment after the onset of ripening stimulated ethylene production.
Exposure of the fruit ripened by propylene to 1-MCP increased ethylene production concomitantly with an increase in 1-aminocyclopropane-1-carboxylate (ACC) synthase activity and ACC content, and prevented a transient decrease in MA-ACS1 transcripts in the pulp tissues.
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9847103 Nakatsuka A, Murachi S, Okunishi H, Shiomi S, Nakano R, Kubo Y, Inaba A: Differential expression and internal feedback regulation of 1-aminocyclopropane-1-carboxylate synthase, 1-aminocyclopropane-1-carboxylate oxidase, and ethylene receptor genes in tomato fruit during development and ripening. Plant Physiol. 1998 Dec;118(4):1295-305.

These increases in mRNAs with ripening were prevented to a large extent by treatment with 1-methylcyclopropene (MCP), an ethylene action inhibitor.
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