Protein Information

Name glyoxalase I
Synonyms Aldoketomutase; GLO 1; GLO1; GLYI; Glx I; Glx1; Glyoxalase I; Glyoxalase I variant…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
17513107 More SS, Vince R: Design, synthesis, and binding studies of bidentate Zn-chelating peptidic inhibitors of glyoxalase-I. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3793-7. Epub 2006 Dec 21.

The known affinity of ethyl acetoacetate (ACC) toward divalent zinc prompted us to attempt its employment as a chelating moiety in the design of glyoxalase-I inhibitors.
32(0,1,1,2) Details