Protein Information

Name phosphodiesterase 11A4
Synonyms PDE11A; PDE11A1; PDE11A2; PDE11A3; Phosphodiesterase 11A; Phosphodiesterase 11A4; cAMP and cGMP phosphodiesterase 11A; Phosphodiesterase 11As…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
18559625 Libe R, Fratticci A, Coste J, Tissier F, Horvath A, Ragazzon B, Rene-Corail F, Groussin L, Bertagna X, Raffin-Sanson ML, Stratakis CA, Bertherat J: Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors. Clin Cancer Res. 2008 Jun 15;14(12):4016-24.

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18419788 Tadjine M, Lampron A, Ouadi L, Horvath A, Stratakis CA, Bourdeau I: Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD). Clin Endocrinol. 2008 Sep;69(3):367-73. Epub 2008 Apr 14.


Genetic alterations of the type 1-alpha regulatory subunit of cAMP-dependent protein kinase A (PRKAR1A) and phosphodiesterase 11A4 (PDE11A) genes have been found in PPNAD.
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