Protein Information

Name thrombin
Synonyms Coagulation factor II; Coagulation factor II variant; F2; F2 protein; F2 protein precursor; Factor II; PT; Prothrombin…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
18687367 Thors B, Halldorsson H, Jonsdottir G, Thorgeirsson G: Mechanism of thrombin mediated eNOS phosphorylation in endothelial cells is dependent on ATP levels after stimulation. Biochim Biophys Acta. 2008 Oct;1783(10):1893-902. Epub 2008 Jul 18.

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17912162 Ferguson JJ, Wilson JM, Diez J: Antithrombotic therapy and the transition to the catheterization laboratory in UA/NSTEMI. Minerva Cardioangiol. 2007 Oct;55(5):529-56.


All available antithrombotic agents act on one (or more) of the four steps of coagulation: platelet activation, platelet aggregation, thrombin generation, and thrombin activity.
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19090933 Moliterno DJ: Advances in antiplatelet therapy for ACS and PCI. J Interv Cardiol. 2008 Dec;21 Suppl 1:S18-24.


Platelet activation and thrombin formation play significant roles in the pathophysiology of acute coronary syndrome.
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20121109 Shen L, Ding M, Zhang L, Jin F, Zhang W, Li D: Expression of Acc-Royalisin gene from royal jelly of chinese honeybee in Escherichia coli and its antibacterial activity. J Agric Food Chem. 2010 Feb 24;58(4):2266-73.

MAR peptide released from the thrombin-cleaved GST-MAR fusion protein has a stronger antibacterial activity than that of GST-MAR fusion protein.
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