Name | caspase 3 |
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Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
Name | ACC |
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CAS | 1-aminocyclopropanecarboxylic acid |
PubMed | Abstract | RScore(About this table) | |
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18601533 | Zhang Z, Lin J, Chu J, Ma Y, Zeng S, Luo Q: Activation of caspase-3 noninvolved in the bystander effect of the herpes simplex virus thymidine kinase gene/ganciclovir (HSV-tk/GCV) system. J Biomed Opt. 2008 May-Jun;13(3):031209. |
3(0,0,0,3) | Details |
20207116 | Magdalan J, Piotrowska A, Gomulkiewicz A, Sozanski T, Podhorska-Okolow M, Szelag A, Dziegiel P: Benzylpenicyllin and hepatocyte cultures. Exp Toxicol Pathol. 2010 Mar 4. Viability of cultured hepatocytes was assessed using the MTT assay, whereas apoptosis processes were evaluated by the electron microscopy, detection of DNA laddering, determination of caspase-3 activity, and measuring annexin V, p53 and Bcl-2 protein concentration. |
protection from alpha-amanitin-induced apoptosis in human 2(0,0,0,2) | Details |
20082303 | Jung JH, Lee JO, Kim JH, Lee SK, You GY, Park SH, Park JM, Kim EK, Suh PG, An JK, Kim HS: suppresses HeLa cell viability via AMPK-induced HSP70 and EGFR down-regulation. J Cell Physiol. 2010 May;223(2):408-14. an AMPK activator, and down-regulated heat shock protein (HSP) 70 and increased the activity of the pro-apoptotic effector, caspase 3. |
2(0,0,0,2) | Details |
19589718 | Chu WF, Wu DM, Liu W, Wu LJ, Li DZ, Xu DY, Wang XF: salivary gland adenoid cystic carcinoma. Oral Oncol. 2009 Nov;45(11):998-1004. Epub 2009 Jul 8. In terms of apoptosis, SFN increased the expression of Bax and decreased the level of Bcl-2 and subsequently triggered release of cytochrome c from mitochondria and activation of caspase-3, but Fas level and caspase-8 activity remained unchanged at all time points. |
induces G2-M arrest and apoptosis in high metastasis cell line of 1(0,0,0,1) | Details |
19036131 | Shirasaki T, Maruya S, Mizukami H, Kakehata S, Kurotaki H, Yagihashi S, Shinkawa H: Effects of small interfering RNA targeting thymidylate synthase on survival of ACC3 cells from salivary adenoid cystic carcinoma. BMC Cancer. 2008 Nov 26;8:348. The effect was associated with an increase in p53, p21, and active caspase-3 and S-phase accumulation. |
1(0,0,0,1) | Details |