Protein Information

Name Telomerase (protein family or complex)
Synonyms Telomerase; Telomerases

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
19029249 Bechard LH, Butuner BD, Peterson GJ, McRae W, Topcu Z, McEachern MJ: Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype. Mol Cell Biol. 2009 Feb;29(3):626-39. Epub 2008 Nov 24.

In Kluyveromyces lactis mutants lacking telomerase, recombinational telomere elongation (RTE) is induced at short telomeres but is suppressed once telomeres are moderately elongated by RTE.
In this study, we generated telomeres composed of either of two types of mutant telomeric repeats, Acc and SnaB, that each alter the binding site for the telomeric protein Rap1.
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18198226 Else T, Giordano TJ, Hammer GD: Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma. J Clin Endocrinol Metab. 2008 Apr;93(4):1442-9. Epub 2008 Jan 15.


MAIN OUTCOME MEASURES: Telomerase activity (telomerase activity protocol assay), alternative telomere lengthening (telomere restriction fragment analysis, telomere associated promyelocyte leukemia bodies) were measured.
1(0,0,0,1) Details