Protein Information

Name c kit
Synonyms C Kit; CD117; CD117 antigen; KIT; KIT oncogene Mast cell growth factor receptor; KIT protein; Mast/stem cell growth factor receptor; Mast/stem cell growth factor receptor precursor…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
20219417 Tang Y, Liang X, Zheng M, Zhu Z, Zhu G, Yang J, Chen Y: Expression of c-kit and Slug correlates with invasion and metastasis of salivary adenoid cystic carcinoma. Oral Oncol. 2010 Apr;46(4):311-6. Epub 2010 Mar 9.

7(0,0,0,7) Details
19360297 Sequeiros-Santiago G, Garcia-Carracedo D, Fresno MF, Suarez C, Rodrigo JP, Gonzalez MV: Oncogene amplification pattern in adenoid cystic carcinoma of the salivary glands. Oncol Rep. 2009 May;21(5):1215-22.


C-Kit, cyclin D1 and EGFR protein levels were immunohistochemically assessed.
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19480697 Luna-Ortiz K, Carmona-Luna T, Cano-Valdez AM, Mosqueda-Taylor A, Herrera-Gomez A, Villavicencio-Valencia V: Adenoid cystic carcinoma of the tongue - clinicopathological study and survival analysis. Head Neck Oncol. 2009 May 29;1(1):15.


ABSTRACT: BACKGROUND: To review the demographic data of a series of adenoid cystic carcinoma (ACC) of the tongue, as well as to analyze c-kit expression, histopathologic patterns, prognostic factors, evolution, recurrences and/or persistence and survival.
2(0,0,0,2) Details
18059225 Seethala RR, Hunt JL, Baloch ZW, Livolsi VA, Leon Barnes E: Adenoid cystic carcinoma with high-grade transformation: a report of 11 cases and a review of the literature. Am J Surg Pathol. 2007 Nov;31(11):1683-94.


Ki-67 and p53 labeling indices were elevated in the high-grade components, though c-kit and cyclin-D1 were not.
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17667537 Di Tommaso L, Kuhn E, Kurrer M, Zettl A, Marx A, Muller-Hermelink HK, Roncalli M, Rosai J: Thymic tumor with adenoid cystic carcinomalike features: a clinicopathologic study of 4 cases. Am J Surg Pathol. 2007 Aug;31(8):1161-7.


The tumor cells showed the following immunophenotype: p63+(3/3), CK34betaE12+(3/3), CD5+ in scattered cells (1/3), CD117- (3/3), chromogranin-(2/2), synaptophysin-(2/2), and CD56- (2/2).
1(0,0,0,1) Details