Protein Information

Name adiponectin
Synonyms 30 kDa adipocyte complemen related protein; 30 kDa adipocyte complement related protein; ACDC; ACRP30; ADIPOQ; APM 1; APM1; Adipocyte C1Q and collagen domain containing…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
17884446 Guo Z, Xia Z, Yuen VG, McNeill JH: Cardiac expression of adiponectin and its receptors in streptozotocin-induced diabetic rats. Metabolism. 2007 Oct;56(10):1363-71.

9(0,0,0,9) Details
19609084 Yamazaki T, Tanimoto M, Gohda T, Ohara I, Hagiwara S, Murakoshi M, Matsumoto M, Kaneko S, Aoki T, Toyoda H, Ishikawa Y, Funabiki K, Horikoshi S, Tomino Y: Combination effects of enalapril and losartan on lipid peroxidation in the kidneys of KK-Ay/Ta mice. Nephron Exp Nephrol. 2009;113(2):e66-76. Epub 2009 Jul 16.


Adiponectin and AMPK might have a role in the pathogenesis of diabetic nephropathy.
7(0,0,0,7) Details
18761357 Rodriguez A, Catalan V, Becerril S, Gil MJ, Mugueta C, Gomez-Ambrosi J, Fruhbeck G: Impaired adiponectin-AMPK signalling in insulin-sensitive tissues of hypertensive rats. Life Sci. 2008 Oct 10;83(15-16):540-9. Epub 2008 Aug 14.

7(0,0,0,7) Details
18946183 Yun JW, Shin ES, Cho SY, Kim SH, Kim CW, Lee TR, Kim BH: The effects of BADGE and caffeine on the time-course response of adiponectin and lipid oxidative enzymes in high fat diet-fed C57BL/6J mice: correlation with reduced adiposity and steatosis. Exp Anim. 2008 Oct;57(5):461-9.

5(0,0,0,5) Details
19169664 Coletta DK, Sriwijitkamol A, Wajcberg E, Tantiwong P, Li M, Prentki M, Madiraju M, Jenkinson CP, Cersosimo E, Musi N, Defronzo RA: Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial. Diabetologia. 2009 Apr;52(4):723-32. Epub 2009 Jan 24.

4(0,0,0,4) Details
18723001 Naitoh R, Miyawaki K, Harada N, Mizunoya W, Toyoda K, Fushiki T, Yamada Y, Seino Y, Inagaki N: Inhibition of GIP signaling modulates adiponectin levels under high-fat diet in mice. Biochem Biophys Res Commun. 2008 Nov 7;376(1):21-5. Epub 2008 Aug 22.

4(0,0,0,4) Details
17577393 Esfandiari F, You M, Villanueva JA, Wong DH, French SW, Halsted CH: S-adenosylmethionine attenuates hepatic lipid synthesis in micropigs fed ethanol with a folate-deficient diet. Alcohol Clin Exp Res. 2007 Jul;31(7):1231-9.


Serum adiponectin, liver transcripts of adiponectin receptor-1 (AdipoR1), and phosphorylated adenosine monophosphate kinase-beta (p-AMPKbeta) were each reduced by ethanol feeding and were sustained at normal levels by SAM supplementation of the ethanol diets.
3(0,0,0,3) Details
17900532 Liu DG, Liu HL, Song TJ, Huang HY, Li X, Tang QQ: Functional expression of the globular domain of human adiponectin in Pichia pastoris. Biochem Biophys Res Commun. 2007 Nov 23;363(3):769-75. Epub 2007 Sep 18.

3(0,0,0,3) Details
19100718 Rivera L, Moron R, Zarzuelo A, Galisteo M: Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats. Biochem Pharmacol. 2009 Mar 15;77(6):1053-63. Epub 2008 Dec 3.


Resveratrol treatment also improved the inflammatory status peculiar to this model, as it increased the concentration of adiponectin and lowered tumor necrosis factor-alpha production in the visceral adipose tissue (VAT) of obese Zucker rats.
1(0,0,0,1) Details
19001513 Richardson MC, Ingamells S, Simonis CD, Cameron IT, Sreekumar R, Vijendren A, Sellahewa L, Coakley S, Byrne CD: Stimulation of lactate production in human granulosa cells by metformin and potential involvement of adenosine 5' monophosphate-activated protein kinase. J Clin Endocrinol Metab. 2009 Feb;94(2):670-7. Epub 2008 Nov 11.


Adiponectin (2.5 microg/ml) had a small but significant effect on lactate output.
1(0,0,0,1) Details
19646421 Brown RE, Wilkinson PM, Imran SA, Wilkinson M: Resistin differentially modulates neuropeptide gene expression and AMP-activated protein kinase activity in N-1 hypothalamic neurons. Brain Res. 2009 Oct 19;1294:52-60. Epub 2009 Jul 29.


Previously we demonstrated that the hypothalamus, and the N-1 hypothalamic neuronal cell line, also expressed several adipokines, including resistin and adiponectin (ADPN).
1(0,0,0,1) Details