| Name | TNFalpha |
|---|---|
| Synonyms | Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2… |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19100718 | Rivera L, Moron R, Zarzuelo A, Galisteo M: Long-term administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats. Biochem Pharmacol. 2009 Mar 15;77(6):1053-63. Epub 2008 Dec 3. treatment also improved the inflammatory status peculiar to this model, as it increased the concentration of adiponectin and lowered tumor necrosis factor-alpha production in the visceral adipose tissue (VAT) of obese Zucker rats. |
1(0,0,0,1) | Details |
| 19890358 | Guo HX, Liu DH, Ma Y, Liu JF, Wang Y, Du ZY, Wang X, Shen JK, Peng HL: Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet. Acta Pharmacol Sin. 2009 Nov;30(11):1505-12. Baicalin also suppressed systemic inflammation by reducing the serum level of tumor necrosis factor alpha. |
1(0,0,0,1) | Details |
| 17725831 | Salas A, Noe V, Ciudad CJ, Romero MM, Remesar X, Esteve M: Short-term oleoyl- treatment affects capacity to manage lipids in rat adipose tissue. BMC Genomics. 2007 Aug 28;8:292. Conversely, Tumour Necrosis Factor (TNFalpha) values showed overexpression (198%). |
1(0,0,0,1) | Details |
| 18071881 | Ates O, Musellim B, Ongen G, Topal-Sarikaya A: Interleukin-10 and tumor necrosis factor-alpha gene polymorphisms in tuberculosis. J Clin Immunol. 2008 May;28(3):232-6. |
1(0,0,0,1) | Details |
| 19673019 | Sanchez R, Levy E, Costea F, Sinnett D: IL-10 and TNF-alpha promoter haplotypes are associated with childhood Crohn's disease location. World J Gastroenterol. 2009 Aug 14;15(30):3776-82. AIM: To determine the distribution and frequencies of the genotypes and haplotypes of the genes encoding for the glucocorticoid receptor (GR), the tumor necrosis factor (TNF)-alpha and the interleukin (IL)-10 in childhood Crohn's disease (CD) and to assess the impact of the corresponding DNA variants on clinical and disease phenotypes. |
1(0,0,0,1) | Details |
| 17965799 | Gonullu G, Basturk B, Evrensel T, Oral B, Gozkaman A, Manavoglu O: Association of breast cancer and cytokine gene polymorphism in Turkish women. Saudi Med J. 2007 Nov;28(11):1728-33. All genotyping of tumor necrosis factor-alpha (TNF-alpha), tumor growth factor-beta1 (TGF-beta1), interleukin (IL)-10, IL-6, and interferon-gamma (IFN-gamma) experiments were performed using polymerase chain reaction sequence-specific primers. |
1(0,0,0,1) | Details |
| 17884446 | Guo Z, Xia Z, Yuen VG, McNeill JH: Cardiac expression of adiponectin and its receptors in streptozotocin-induced diabetic rats. Metabolism. 2007 Oct;56(10):1363-71. Plasma and cardiac interleukin 6 and plasma tumor necrosis factor alpha (TNF-alpha) were assayed by enzyme-linked immunosorbent assay. |
1(0,0,0,1) | Details |
| 20305143 | Dickinson AM, Pearce KF, Norden J, O'Brien SG, Holler E, Bickeboller H, Balavarca Y, Rocha V, Kolb HJ, Hromadnikova I, Sedlacek P, Niederwieser D, Brand R, Ruutu T, Apperley J, Szydlo R, Goulmy E, Siegert W, de Witte T, Gratwohl A: Impact of genomic risk factors on outcome after hematopoietic stem cell transplantation for patients with chronic myeloid leukemia. Haematologica. 2010 Mar 19. DESIGN AND METHODS: In this study, we assessed the effect of single nucleotide polymorphisms in genes for interleukin 1 receptor antagonist (IL1RN), interleukin (IL) 4 (IL4), IL6, IL10, interferon (IFN) IFNG, tumor necrosis factor (TNF) and cell surface receptors TNF receptor II (TNFRSFIB), receptor (VDR) and estrogen receptor alpha (ESR1) in a homogeneous cohort of 228 HLA identical sibling transplantations for chronic myeloid leukemia. |
1(0,0,0,1) | Details |
| 19587531 | Zang G, Miao L, Mu Y, Qiao C, Liu J, Ke X, Zheng C, Sun H: Adenoviral mediated transduction of adenoid cystic carcinoma by human TRAIL gene driven with hTERT tumor specific promoter induces apoptosis. Cancer Biol Ther. 2009 May;8(10):966-72. To test this concept, we selected tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and the human telomerase reverse transcriptase (hTERT) promoter. |
1(0,0,0,1) | Details |
| 19914257 | Ceylan-Isik AF, Zhao P, Zhang B, Xiao X, Su G, Ren J: Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis. J Mol Cell Cardiol. 2010 Feb;48(2):367-78. Epub 2009 Nov 13. Oxidative stress, activation of mitogen-activated protein kinase pathways (ERK, JNK and p38), ER stress, autophagy and inflammatory markers iNOS and TNFalpha were evaluated. |
2(0,0,0,2) | Details |
| 18427872 | Ates O, Hatemi G, Hamuryudan V, Topal-Sarikaya A: Tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphisms in Turkish rheumatoid arthritis patients. Clin Rheumatol. 2008 Oct;27(10):1243-8. Epub 2008 Apr 22. |
2(0,0,0,2) | Details |
| 18028781 | Zhang B, Guan CC, Chen WT, Zhang P, Yan M, Shi JH, Qin CL, Yang Q: A20 inhibits human salivary adenoid cystic carcinoma cells invasion via blocking nuclear factor-kappaB activation. Chin Med J. 2007 Oct 20;120(20):1830-5. BACKGROUND: A20, also known as tumor necrosis factor alpha induced protein 3 (TNFaip3), is a cytoplasmic zinc finger protein that inhibits nuclear factor kappa-B (NF-kappaB) activity and prevents tumor necrosis factor (TNF)-mediated programmed cell death. |
2(0,0,0,2) | Details |
| 20041784 | Cho K, Kim SJ, Park SH, Kim S, Park T: Protective effect of Codonopsis lanceolata root extract against alcoholic fatty liver in the rat. J Med Food. 2009 Dec;12(6):1293-301. Chronic alcohol consumption up-regulated the hepatic expression of genes involved in inflammation, fatty acid synthesis, and metabolism, including tumor necrosis factor alpha (TNFalpha), liver X receptor alpha (LXRalpha), sterol regulatory element-binding protein (SREBP)-1c, fatty acid synthase, acetyl-coenzyme A carboxylase alpha (ACC), stearoyl-coenzyme A desaturase 1, 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR), and low-density lipoprotein receptor (LDLR). |
2(0,0,0,2) | Details |
| 18705845 | Mirahmadian M, Kalantar F, Heidari G, Safdarian L, Mansouri R, Amirzargar AA: Association of tumor necrosis factor-alpha and interleukin-10 gene polymorphisms in Iranian patients with pre-eclampsia. Am J Reprod Immunol. 2008 Aug;60(2):179-85. |
2(0,0,0,2) | Details |
| 17988266 | Coppo R, Amore A, Chiesa M, Lombardo F, Cirina P, Andrulli S, Passerini P, Conti G, Peruzzi L, Giraudi R, Messina M, Segoloni G, Ponticelli C: Serological and genetic factors in early recurrence of IgA nephropathy after renal transplantation. Clin Transplant. 2007 Nov-Dec;21(6):728-37. METHODS: Sixty-one transplanted patients who had IgAN as an original disease (30 with biopsy-proved early recurrence, median 2.9 yr post-transplant), and 120 controls, were investigated for aberrantly glycosylated IgA1, IgA binding to mesangial matrix, macromolecular IgA (IgA/fibronectin and uteroglobulin/IgA/fibronectin complexes), and polymorphisms of cytokines [tumor necrosis factor alpha (TNFalpha), interleukin 10 (IL-10), IL-6, interferon gamma and transforming growth factor beta 1] and renin-angiotensin system (angiotensinogen converting enzyme, angiotensin II receptor 1, and angiotensinogen) genes. |
2(0,0,0,2) | Details |