Protein Information

Name NKCC2
Synonyms BSC 1; BSC1; Bumetanide sensitive NA K 2Cl cotransporter; Bumetanide sensitive sodium (potassium) chloride cotransporter 2; Kidney specific Na K Cl symporter; NKCC 2; NKCC2; SLC12A1…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
19176702 Cook N, Fraser SA, Katerelos M, Katsis F, Gleich K, Mount PF, Steinberg GR, Levidiotis V, Kemp BE, Power DA: Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells. Am J Physiol Renal Physiol. 2009 Apr;296(4):F801-9. Epub 2009 Jan 28.


The energy-sensing kinase AMP-activated protein kinase (AMPK) is associated with the sodium-potassium-chloride cotransporter NKCC2 in the kidney and phosphorylates it on a regulatory site in vitro.
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