| Name | malonyl CoA decarboxylase |
|---|---|
| Synonyms | MCD; MLYCD; Malonyl CoA decarboxylase; Malonyl Coenzyme A decarboxylase; hMCD; Malonyl CoA decarboxylases; Malonyl Coenzyme A decarboxylases; hMCDs |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18561258 | Pimenta AS, Gaidhu MP, Habib S, So M, Fediuc S, Mirpourian M, Musheev M, Curi R, Ceddia RB: Prolonged exposure to impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells. J Cell Physiol. 2008 Nov;217(2):478-85. Interestingly, this occurred despite significant increases in AMPK ( approximately 2.5-fold) and ACC ( approximately 3-fold) phosphorylation and in malonyl-CoA decarboxylase activity ( approximately 38-60%). |
1(0,0,0,1) | Details |
| 18719599 | Lane MD, Wolfgang M, Cha SH, Dai Y: Regulation of food intake and energy expenditure by hypothalamic Int J Obes. 2008 Sep;32 Suppl 4:S49-54. Stereotactic delivery of a viral malonyl-CoA decarboxylase (MCD) vector into the ventral hypothalamus lowers and increases food intake. |
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| 18614968 | Yatscoff MA, Jaswal JS, Grant MR, Greenwood R, Lukat T, Beker DL, Rebeyka IM, Lopaschuk GD: Myocardial hypertrophy and the maturation of fatty acid oxidation in the newborn human heart. Pediatr Res. 2008 Dec;64(6):643-7. We have previously demonstrated that the decrease in is due to increased activity of malonyl CoA decarboxylase (MCD), and decreased activity of carboxylase (ACC), enzymes which degrade and synthesize respectively. |
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| 18485240 | Germani D, Puglianiello A, Cianfarani S: Uteroplacental insufficiency down regulates insulin receptor and affects expression of key enzymes of long-chain fatty acid (LCFA) metabolism in skeletal muscle at birth. Cardiovasc Diabetol. 2008 May 18;7:14. Muscle of the posterior limb was dissected at birth and processed by real-time RT-PCR to analyze the expression of insulin receptor, ACCalpha, ACCbeta (acetyl-CoA carboxylase alpha and beta subunits), ACS (acyl-CoA synthase), AMPK (AMP-activated protein kinase, alpha2 catalytic subunit), CPT1B palmitoyltransferase-1 beta subunit), MCD (malonyl-CoA decarboxylase) in 14 sham and 8 IUGR pups. |
1(0,0,0,1) | Details |