| Name | NR2B |
|---|---|
| Synonyms | GRIN2B; Glutamate [NMDA] receptor subunit epsilon 2; Glutamate [NMDA] receptor subunit epsilon 2 precursor; N methyl D aspartate receptor subtype 2B; N methyl D aspartate receptor subunit 2B; N methyl D aspartate receptor subunit 3; NMDAR2B; NR2B… |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17470281 | Wu LJ, Xu H, Ren M, Cao X, Zhuo M: Pharmacological isolation of postsynaptic currents mediated by NR2A- and NR2B-containing NMDA receptors in the anterior cingulate cortex. Mol Pain. 2007 Apr 30;3:11. |
2(0,0,0,2) | Details |
| 19664265 | Toyoda H, Zhao MG, Ulzhofer B, Wu LJ, Xu H, Seeburg PH, Sprengel R, Kuner R, Zhuo M: Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex. Mol Pain. 2009 Aug 10;5:46. (NMDA) receptors in the ACC are critical for the induction of LTP, including both NR2A and NR2B subunits. |
1(0,0,0,1) | Details |
| 17522019 | Shum FW, Wu LJ, Zhao MG, Toyoda H, Xu H, Ren M, Pinaud R, Ko SW, Lee YS, Kaang BK, Zhuo M: Alteration of cingulate long-term plasticity and behavioral sensitization to inflammation by environmental enrichment. Learn Mem. 2007 Apr 10;14(4):304-12. Print 2007 Apr. The increased NMDA receptor NR2B/NR2A subunits current ratio is associated with the plasticity seen in the ACC while total protein levels remain unchanged. |
1(0,0,0,1) | Details |
| 19324536 | Arnold PD, Macmaster FP, Richter MA, Hanna GL, Sicard T, Burroughs E, Mirza Y, Easter PC, Rose M, Kennedy JL, Rosenberg DR: Glutamate receptor gene (GRIN2B) associated with reduced anterior cingulate glutamatergic concentration in pediatric obsessive-compulsive disorder. Psychiatry Res. 2009 May 15;172(2):136-9. Epub 2009 Mar 25. These results suggest that GRIN2B may be associated with Glx in the ACC, a region consistently implicated in OCD. |
7(0,0,1,2) | Details |
| 18803856 | Ko SW, Wu LJ, Shum F, Quan J, Zhuo M: Cingulate NR2B receptors contribute to morphine-induced analgesic tolerance. Mol Brain. 2008 Jun 17;1(1):2. |
6(0,0,0,6) | Details |
| 19208366 | Fan J, Wu X, Cao Z, Chen S, Owyang C, Li Y: Up-regulation of anterior cingulate cortex NR2B receptors contributes to visceral pain responses in rats. Gastroenterology. 2009 May;136(5):1732-40.e3. Epub 2009 Feb 6. |
6(0,0,0,6) | Details |
| 19445686 | Zhao MG, Toyoda H, Wang YK, Zhuo M: Enhanced synaptic long-term potentiation in the anterior cingulate cortex of adult wild mice as compared with that in laboratory mice. Mol Brain. 2009 May 16;2(1):11. Genetic enhancement of NMDA receptor function by overexpressing NR2B subunit significantly enhances hippocampal long-term potentiation (LTP), behavioral learning as well as persistent pain. |
4(0,0,0,4) | Details |
| 19695778 | Li TT, Ren WH, Xiao X, Nan J, Cheng LZ, Zhang XH, Zhao ZQ, Zhang YQ: NR2A and NR2B receptors in the rostral anterior cingulate cortex contribute to pain-related aversion in male rats. Pain. 2009 Nov;146(1-2):183-93. Epub 2009 Aug 19. |
4(0,0,0,4) | Details |
| 18410946 | Chen L, Liu JC, Zhang XN, Guo YY, Xu ZH, Cao W, Sun XL, Sun WJ, Zhao MG: Down-regulation of NR2B receptors partially contributes to analgesic effects of Gentiopicroside in persistent inflammatory pain. Neuropharmacology. 2008 Jun;54(8):1175-81. Epub 2008 Mar 25. |
4(0,0,0,4) | Details |