| Name | liver X receptor alpha |
|---|---|
| Synonyms | LXR a; LXR a; LXRA; Liver X receptor alpha; NR1H3; Nuclear orphan receptor LXR alpha; Oxysterols receptor LXR alpha; RLD 1… |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19954950 | Kim HJ, Yuan J, Norris K, Vaziri ND: High-calorie diet partially ameliorates dysregulation of intrarenal lipid metabolism in remnant kidney. J Nutr Biochem. 2009 Nov 30. The CRF group consuming a regular diet exhibited growth retardation; azotemia; proteinuria; glomerulosclerosis; tubulointerstitial injury; heavy lipid accumulation in the remnant kidney; up-regulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), ATP-binding cassette transporter-1 (ABCA1), liver X receptor (LXR) alpha/beta, carbohydrate-responsive element binding protein (ChREBP) and acyl- carboxylase (ACC); and down-regulation of peroxisome proliferator-activated receptor-alpha (PPAR-alpha), palmitoyltransferase-1 (CPT1) and liver-type fatty acid binding protein (L-FABP). |
1(0,0,0,1) | Details |
| 20041784 | Cho K, Kim SJ, Park SH, Kim S, Park T: Protective effect of Codonopsis lanceolata root extract against alcoholic fatty liver in the rat. J Med Food. 2009 Dec;12(6):1293-301. Chronic alcohol consumption up-regulated the hepatic expression of genes involved in inflammation, fatty acid synthesis, and metabolism, including tumor necrosis factor alpha (TNFalpha), liver X receptor alpha (LXRalpha), sterol regulatory element-binding protein (SREBP)-1c, fatty acid synthase, acetyl-coenzyme A carboxylase alpha (ACC), stearoyl-coenzyme A desaturase 1, 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR), and low-density lipoprotein receptor (LDLR). |
1(0,0,0,1) | Details |
| 18975056 | Han C, Wang J, Li L, Wang L, Zhang Z: The role of LXR alpha in goose primary hepatocyte lipogenesis. Mol Cell Biochem. 2009 Feb;322(1-2):37-42. Epub 2008 Oct 31. In this study, we investigate the role of liver X receptor alpha (LXR alpha) in lipogenesis in geese in order to understand the differences in hepatic steatosis mechanisms between mammals and waterfowl. |
1(0,0,0,1) | Details |
| 18794597 | Morgan K, Uyuni A, Nandgiri G, Mao L, Castaneda L, Kathirvel E, French SW, Morgan TR: Altered expression of transcription factors and genes regulating lipogenesis in liver and adipose tissue of mice with high fat diet-induced obesity and nonalcoholic fatty liver disease. Eur J Gastroenterol Hepatol. 2008 Sep;20(9):843-54. Hepatic expression of sterol regulatory element-binding protein-1c, carbohydrate response element-binding protein, liver X receptor-alpha, carboxylase (ACC), and fatty acid synthase (FAS) decreased during fasting in SF and HF mice; however, FAS expression and protein content were higher in the liver of fasted HF mice than of fasted SF mice. |
1(0,0,0,1) | Details |
| 18070748 | Moon HS, Chung CS, Lee HG, Kim TG, Choi YJ, Cho CS: Inhibitory effect of (-)- on lipid accumulation of 3T3-L1 cells. Obesity (Silver Spring). 2007 Nov;15(11):2571-82. During this period, greatly decreased expression of the adipocyte marker proteins peroxisome proliferator-activated receptor gamma2 (PPARgamma2) and liver X receptor (LXR)-alpha. |
1(0,0,0,1) | Details |