Protein Information

Name 4E BP1
Synonyms 4E BP1; 4EBP1; BP 1; EIF 4E binding protein 1; EIF4EBP1; Eukaryotic translation initiation factor 4E binding protein 1; PHAS 1; PHAS I…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
18187610 Thomson DM, Fick CA, Gordon SE: AMPK activation attenuates S6K1, 4E-BP1, and eEF2 signaling responses to high-frequency electrically stimulated skeletal muscle contractions. J Appl Physiol. 2008 Mar;104(3):625-32. Epub 2008 Jan 10.

3(0,0,0,3) Details
19662644 Huang CH, Tsai SJ, Wang YJ, Pan MH, Kao JY, Way TD: EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells. Mol Nutr Food Res. 2009 Sep;53(9):1156-65.


The activation of AMPK suppressed downstream substrates, such as mammalian target of rapamycin (mTOR) and eukaryotic initiation factor 4E-binding protein-1 (4E-BP1) and a general decrease in mRNA translation.
1(0,0,0,1) Details