Protein Information

Name glutamic acid decarboxylase
Synonyms 65 kDa glutamic acid decarboxylase; GAD 2; GAD 65; GAD2; GAD65; Glutamate decarboxylase 2; Glutamate decarboxylase 2 (pancreas); Glutamate decarboxylase 65 kDa isoform…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
18221440 Bowden SA, Hoffman RP: Triple diabetes: coexistence of type 1 diabetes mellitus and a novel mutation in the gene responsible for MODY3 in an overweight adolescent. Pediatr Diabetes. 2008 Apr;9(2):162-4. Epub 2008 Jan 19.


Immunologic studies showed positive islet cell (29 U/mL, normal <1.0) and glutamic acid decarboxylase-65 (0.9 U/mL, normal <0.5) antibodies.
1(0,0,0,1) Details
18312583 Carta AR, Moreno CC, Cadoni C, Tronci E, Di Chiara G: Long-term increase in GAD67 mRNA expression in the central amygdala of rats sensitized by drugs and stress. Eur J Neurosci. 2008 Mar;27(5):1220-30. Epub 2008 Feb 29.

Thereafter, changes in the expression of glutamic acid decarboxylase (GAD) 67 mRNA were estimated by in situ hybridization in the central nucleus of the amygdala (CeA), basolateral amygdala (BLA), dorsolateral striatum (dLStr), nucleus accumbens shell (AcS) and core (AcC).
6(0,0,1,1) Details
19321177 Thompson M, Weickert CS, Wyatt E, Webster MJ: Decreased glutamic acid decarboxylase (67) mRNA expression in multiple brain areas of patients with schizophrenia and mood disorders. J Psychiatr Res. 2009 Jul;43(11):970-7. Epub 2009 Mar 24.

2(0,0,0,2) Details
20009027 Catalano PN, Di Giorgio N, Bonaventura MM, Bettler B, Libertun C, Lux-Lantos VA: Lack of functional GABA (B) receptors alters GnRH physiology and sexual dimorphic expression of GnRH and GAD-67 in the brain. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E683-96. Epub 2009 Dec 15.


Glutamic acid decarboxylase-67 (GAD-67) mRNA was measured by qRT-PCR in POA-AH, MBH-PH, and CT.
1(0,0,0,1) Details