| Name | CPT1 |
|---|---|
| Synonyms | CPT 2; CPT 1; CPT1; CPT II; CPT2; CPTASE; Carnitine palmitoyltransferase 2; Carnitine palmitoyltransferase II… |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19694967 | Schreurs M, Kuipers F, van der Leij FR: Regulatory enzymes of mitochondrial beta-oxidation as targets for treatment of the metabolic syndrome. Obes Rev. 2009 Aug 20. The -activated protein kinase-ACC-CPT1 axis tightly regulates mitochondrial long-chain fatty acid oxidation. |
8(0,0,0,8) | Details |
| 17515867 | Puglianiello A, Germani D, Antignani S, Tomba GS, Cianfarani S: Changes in the expression of hypothalamic lipid sensing genes in rat model of intrauterine growth retardation (IUGR). Pediatr Res. 2007 Apr;61(4):433-7. The enzyme palmitoyltransferase-1 (CPT1) regulates long-chain fatty acid (LCFA) entry into mitochondria, where LCFA undergo beta-oxidation. |
4(0,0,0,4) | Details |
| 19954950 | Kim HJ, Yuan J, Norris K, Vaziri ND: High-calorie diet partially ameliorates dysregulation of intrarenal lipid metabolism in remnant kidney. J Nutr Biochem. 2009 Nov 30. The CRF group consuming a regular diet exhibited growth retardation; azotemia; proteinuria; glomerulosclerosis; tubulointerstitial injury; heavy lipid accumulation in the remnant kidney; up-regulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), ATP-binding cassette transporter-1 (ABCA1), liver X receptor (LXR) alpha/beta, carbohydrate-responsive element binding protein (ChREBP) and acyl- carboxylase (ACC); and down-regulation of peroxisome proliferator-activated receptor-alpha (PPAR-alpha), palmitoyltransferase-1 (CPT1) and liver-type fatty acid binding protein (L-FABP). |
2(0,0,0,2) | Details |
| 18761357 | Rodriguez A, Catalan V, Becerril S, Gil MJ, Mugueta C, Gomez-Ambrosi J, Fruhbeck G: Impaired adiponectin-AMPK signalling in insulin-sensitive tissues of hypertensive rats. Life Sci. 2008 Oct 10;83(15-16):540-9. Epub 2008 Aug 14. The expression of AdipoR1 and AdipoR2, carboxylase (ACC), as well as palmitoyl transferase 1 (CPT1), were increased in skeletal muscle of SHR. |
1(0,0,0,1) | Details |
| 19588182 | Morise A, Thomas C, Landrier JF, Besnard P, Hermier D: Hepatic lipid metabolism response to dietary fatty acids is differently modulated by PPARalpha in male and female mice. Eur J Nutr. 2009 Dec;48(8):465-73. Epub 2009 Jul 9. When compared to SFA-fed KO mice, steatosis was twice lower in KO mice fed on ALA, despite the absence of dietary effect on plasma TG, CPT1 and ACO activities, or ACC and FAS expression. |
2(0,0,0,2) | Details |
| 18719599 | Lane MD, Wolfgang M, Cha SH, Dai Y: Regulation of food intake and energy expenditure by hypothalamic Int J Obes. 2008 Sep;32 Suppl 4:S49-54. is an inhibitor of transferase-1 (CPT1), an outer mitochondrial membrane enzyme that regulates entry into, and oxidation of fatty acids, by mitochondria. |
1(0,0,0,1) | Details |
| 18946183 | Yun JW, Shin ES, Cho SY, Kim SH, Kim CW, Lee TR, Kim BH: The effects of BADGE and on the time-course response of adiponectin and lipid oxidative enzymes in high fat diet-fed C57BL/6J mice: correlation with reduced adiposity and steatosis. Exp Anim. 2008 Oct;57(5):461-9. ACC phosphorylation and palmitoyl-transferase-1 (CPT1) activity have been shown to be rate controlling factors in fatty acid oxidation. |
1(0,0,0,1) | Details |