Protein Information

Name straight chain acyl CoA oxidase
Synonyms ACOX; ACOX palmitoyl CoA oxidase Acyl CoA oxidase straight chain; ACOX palmitoyl Coenzyme A oxidase Acyl Coenzyme A oxidase straight chain; ACOX 1; ACOX1; ACOX1 Acyl CoA oxidase palmitoyl peroxidase Acyl CoA oxidase; ACOX1 Acyl Coenzyme A oxidase palmitoyl peroxidase Acyl Coenzyme A oxidase; AOX…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
17671740 Kohjima M, Enjoji M, Higuchi N, Kato M, Kotoh K, Yoshimoto T, Fujino T, Yada M, Yada R, Harada N, Takayanagi R, Nakamuta M: Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. Int J Mol Med. 2007 Sep;20(3):351-8.


The target genes for real-time PCR analysis were as follows: acetyl-CoA carboxylase (ACC) 1, ACC2, fatty acid synthase (FAS), sterol regulatory element-binding protein 1c (SREBP-1c), and adipose differentiation-related protein (ADRP) for evaluation of de novo synthesis and uptake of fatty acids; carnitine palmitoyltransferase 1a; (CPT1a), long-chain acyl-CoA dehydrogenase (LCAD), long-chain L-3-hydroxyacylcoenzyme A dehydrogenase alpha (HADHalpha), uncoupling protein 2 (UCP2), straight-chain acyl-CoA oxidase (ACOX), branched-chain acyl-CoA oxidase (BOX), cytochrome P450 2E1 (CYP2E1), CYP4A11, and peroxisome proliferator-activated receptor (PPAR) alpha for oxidation in the mitochondria, peroxisomes and microsomes; superoxide dismutase (SOD), catalase, and glutathione synthetase (GSS) for antioxidant pathways; and diacylglycerol O-acyltransferase 1 (DGAT1), PPARgamma, and hormone-sensitive lipase (HSL) for triglyceride synthesis and catalysis.
2(0,0,0,2) Details
20139613 Yuan HD, Yuan HY, Chung SH, Jin GZ, Piao GC: An active part of Artemisia sacrorum Ledeb. attenuates hepatic lipid accumulation through activating AMP-activated protein kinase in human HepG2 cells. Biosci Biotechnol Biochem. 2010 Feb 23;74(2):322-8. Epub 2010 Feb 7.


At the same time, 95% EE significantly increased the gene expression of acyl CoA oxidase (ACOX) in a time- and dose-dependent manner.
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17704960 Tang X, Ma H, Zou S, Chen W: Effects of dehydroepiandrosterone (DHEA) on hepatic lipid metabolism parameters and lipogenic gene mRNA expression in broiler chickens. Lipids. 2007 Nov;42(11):1025-33. Epub 2007 Aug 18.


The expression of peroxisome proliferators-activated receptor alpha (PPARalpha) and carnitine palmitoyl transferase I (CPTI) mRNA was decidedly enhanced following treatment with DHEA, and a similar tendency was also observed in the expression of acyl-Coenzyme A oxidase 1 (ACOX1).
1(0,0,0,1) Details