| Name | carnitine palmitoyltransferase I |
|---|---|
| Synonyms | CPT I; CPT 1; CPT1; CPT1 L; CPT1A; CPTI L; Carnitine palmitoyltransferase 1A; Carnitine palmitoyltransferase I… |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20036965 | Wang C, Rajput S, Watabe K, Liao DF, Cao D: carboxylase-a as a novel target for cancer therapy. Front Biosci (Schol Ed). 2010 Jan 1;2:515-26. is a critical bi-functional molecule, i.e., a substrate of fatty acid synthase (FAS) for acyl chain elongation (fatty acid synthesis) and an inhibitor of carnitine palmitoyltransferase I (CPT-I) for fatty acid beta-oxidation. |
1(0,0,0,1) | Details |
| 18850226 | Lee MS, Kwun IS, Kim Y: increases lipolysis through up-regulation of the lipolytic gene expression and down-regulation of the adipogenic gene expression in 3T3-L1 adipocytes. Genes Nutr. 2008 Feb;2(4):327-30. The mRNA level of carnitine palmitoyltransferase I-a, a component of the fatty-acid shuttle system involved in the mitochondrial oxidation of long-chain fatty acids, was also significantly elevated by EPA (P < 0.05). |
1(0,0,0,1) | Details |
| 19878707 | Cho KH, Kim HJ, Kamanna VS, Vaziri ND: improves renal lipid metabolism and slows progression in chronic kidney disease. Biochim Biophys Acta. 2010 Jan;1800(1):6-15. Epub 2009 Oct 28. RESULTS: CRF resulted in hypertension, proteinuria, renal tissue lipid accumulation, up-regulation of scavenger receptor A1 (SR-A1), acyl-CoA cholesterol acyltransferase-1 (ACAT1), carbohydrate-responsive element binding protein (ChREBP), fatty acid synthase (FAS), acyl- carboxylase (ACC), liver X receptor (LXR), ATP binding cassette (ABC) A-1, ABCG-1, and SR-B1 and down-regulation of sterol responsive element binding protein-1 (SREBP-1), SREBP-2, HMG- reductase, PPAR-alpha, fatty acid binding protein (L-FABP), and CPT1A. |
1(0,0,0,1) | Details |
| 18539180 | Lee HG, Kumar KS, Soh JR, Cha YS, Kang SH: Ultra-fast simultaneous detection of obesity-related coenzymes in mice using microchip electrophoresis with a LIF detector. Anal Chim Acta. 2008 Jun 30;619(1):94-100. Epub 2008 Jan 15. Hepatic acyl- synthetase (ACS), carnitine palmitoyltransferase-I (CPT-I) and carboxylase (ACC) are coenzymes associated with the genetic type of obesity in animal models. |
1(0,0,0,1) | Details |
| 17905647 | Priore P, Giudetti AM, Natali F, Gnoni GV, Geelen MJ: Metabolism and short-term metabolic effects of conjugated linoleic acids in rat hepatocytes. Biochim Biophys Acta. 2007 Oct;1771(10):1299-307. Epub 2007 Aug 22. In isolated mitochondria CLA- were poorer substrates than LA- for carnitine palmitoyltransferase-I (CPT-I) activity. |
1(0,0,0,1) | Details |