Protein Information

Name AC1
Synonyms AC1; ADCY 1; ADCY1; ATP pyrophosphate lyase; ATP pyrophosphate lyase 1; Adenylate cyclase 1; Adenylate cyclase type 1; Adenylate cyclase type I…

Compound Information

Name ACC
CAS 1-aminocyclopropanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
18434517 Wang H, Wu LJ, Zhang F, Zhuo M: Roles of calcium-stimulated adenylyl cyclase and calmodulin-dependent protein kinase IV in the regulation of FMRP by group I metabotropic glutamate receptors. J Neurosci. 2008 Apr 23;28(17):4385-97.


Using genetic approaches, we found that Ca (2+)/calmodulin-stimulated adenylyl cyclase 1 (AC1) and calcium/calmodulin-dependent kinase IV (CaMKIV) contribute to the upregulation of FMRP induced by stimulating group I mGluRs.
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18632948 Xu H, Wu LJ, Wang H, Zhang X, Vadakkan KI, Kim SS, Steenland HW, Zhuo M: Presynaptic and postsynaptic amplifications of neuropathic pain in the anterior cingulate cortex. J Neurosci. 2008 Jul 16;28(29):7445-53.


Finally, we found that both presynaptic and postsynaptic changes after nerve injury were absent in genetic mice lacking calcium-stimulated adenylyl cyclase 1 (AC1).
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