Name | citrate lyase (protein family or complex) |
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Synonyms | Citrate lyase; Citrate lyases |
Name | ACC |
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CAS | 1-aminocyclopropanecarboxylic acid |
PubMed | Abstract | RScore(About this table) | |
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19427916 | Proszkowiec-Weglarz M, Richards MP, Humphrey BD, Rosebrough RW, McMurtry JP: AMP-activated protein kinase and carbohydrate response element binding protein: a study of two potential regulatory factors in the hepatic lipogenic program of broiler chickens. Comp Biochem Physiol B Biochem Mol Biol. 2009 Sep;154(1):68-79. Epub 2009 May 8. The mRNA levels of malic enzyme (ME), ATP-citrate lyase (ACL), acetyl-CoA carboxylase alpha (ACCalpha), fatty acid synthase (FAS), stearoyl-CoA desaturase-1 (SCD-1) and thyroid hormone responsive Spot 14 (Spot 14) declined in response to fasting. |
1(0,0,0,1) | Details |
17762189 | Mailloux R, Lemire J, Appanna V: Aluminum-induced mitochondrial dysfunction leads to lipid accumulation in human hepatocytes: a link to obesity. Cell Physiol Biochem. 2007;20(5):627-38. Electrophoretic and immunoblot analyses pointed to increased activities and expression of lipogenic enzymes such as dehydrogenase (G3PDH), carboxylase (ACC) and ATP-citrate lyase (CL) in the hepatocytes exposed to Al, and a sharp diminution of enzymes mediating oxidative phosphorylation. |
1(0,0,0,1) | Details |
17984485 | Jakus PB, Sandor A, Janaky T, Farkas V: Cooperation between BAT and WAT of rats in thermogenesis in response to cold, and the mechanism of accumulation in BAT during reacclimation. J Lipid Res. 2008 Feb;49(2):332-9. Epub 2007 Nov 5. Of the many proteins involved in the metabolic response, two lipogenic enzymes, carboxylase (ACC) and ATP-citrate lyase, were found to play a pervasive role and studied in detail. |
1(0,0,0,1) | Details |
17391151 | Clapham JC, Arch JR: Thermogenic and metabolic antiobesity drugs: rationale and opportunities. Diabetes Obes Metab. 2007 May;9(3):259-75. ATP citrate lyase, fatty acid synthase, carboxylase (ACC)], fatty acid interconversion [stearoyl-CoA desaturase (SCD)] and triglyceride synthesis (e.g. acyl-CoA : diacylglycerol acyltransferase) may all be thermogenic. |
1(0,0,0,1) | Details |