| Name | insulin receptor |
|---|---|
| Synonyms | CD220; CD220 antigen; HHF 5; HHF5; INSR; INSR protein; IR; Insulin receptor… |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18485240 | Germani D, Puglianiello A, Cianfarani S: Uteroplacental insufficiency down regulates insulin receptor and affects expression of key enzymes of long-chain fatty acid (LCFA) metabolism in skeletal muscle at birth. Cardiovasc Diabetol. 2008 May 18;7:14. |
5(0,0,0,5) | Details |
| 18469022 | Stoppa GR, Cesquini M, Roman EA, Prada PO, Torsoni AS, Romanatto T, Saad MJ, Velloso LA, Torsoni MA: Intracerebroventricular injection of inhibits hypothalamic AMPK and modulates feeding behavior and peripheral insulin signaling. J Endocrinol. 2008 Jul;198(1):157-68. Epub 2008 May 9. Concordantly, insulin receptor (IR), IR substrate type 1 (IRS1), IRS2, and protein kinase B (AKT) phosphorylation in adipose tissue and skeletal muscle was improved by ICV treatment. |
1(0,0,0,1) | Details |
| 19158325 | Berggreen C, Gormand A, Omar B, Degerman E, Goransson O: Protein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes. Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E635-46. Epub 2009 Jan 21. Pretreatment of primary rat and 3T3L1 adipocytes with Akti resulted in dose-dependent inhibition of PKB phosphorylation and activation in response to insulin, without affecting upstream insulin signaling [insulin receptor (IR), insulin receptor substrate (IRS)] or the insulin-induced phosphoinositide 3-kinase (PI3K)-dependent activation of the ERK/p90 ribosomal kinase (RSK) pathway. |
1(0,0,0,1) | Details |
| 18070748 | Moon HS, Chung CS, Lee HG, Kim TG, Choi YJ, Cho CS: Inhibitory effect of (-)- on lipid accumulation of 3T3-L1 cells. Obesity (Silver Spring). 2007 Nov;15(11):2571-82. Western blot analysis was used to detect -activated protein kinase (AMPK) activation and phosphorylation of its substrate, carboxylase (ACC), and expression of insulin (INS) receptor, INS receptor substrate-1 (IRS-1), and adipocyte marker proteins. |
1(0,0,0,1) | Details |