Protein Information

Name endothelin 1
Synonyms EDN 1; EDN1; ET1; Endothelin 1; Endothelin 1 precursor; PPET 1; PPET1; Preproendothelin 1…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
11078329 Khiat A, Fournier A, Lubell W, Boulanger Y: Conformational analysis of endothelin-1 analogs with indolizidinone amino acids incorporated at the C-terminus. J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S33-5.

2(0,0,0,2) Details
12005183 Xiao GN, Guan YY, He H: Effects of Cl- channel blockers on endothelin-1-induced proliferation of rat vascular smooth muscle cells. Life Sci. 2002 Mar 29;70(19):2233-41.

2(0,0,0,2) Details
15838260 Dai Y, Zhang J: Chloride efflux is involved in ET-1 and 5-HT-induced contraction in rabbit basilar artery. J Cardiovasc Pharmacol. 2004 Nov;44 Suppl 1:S125-8.


We tested the effect of endothelin-1 and 5-hydroxytryptamine on isometric tension in rabbit basilar artery by inhibition of Na+-K+-2Cl- co-transporter and Cl-/HCO3- exchanger to decrease Cl-, by decreasing extracellular Cl- concentration, and by blocking Cl- channels using Cl- channel inhibitors.
2(0,0,0,2) Details