Protein Information

Name angiotensin II
Synonyms AGT; ANG II; ANHU; Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensinogen precursor; SERPINA 8…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
10555568 Nabel C, Schweda F, Riegger GA, Kramer BK, Kurtz A: Chloride channel blockers attenuate the inhibition of renin secretion by angiotensin II. Pflugers Arch. 1999 Oct;438(5):694-9.

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14506073 Steendahl J, Holstein-Rathlou NH, Sorensen CM, Salomonsson M: Effects of chloride channel blockers on rat renal vascular responses to angiotensin II and norepinephrine. Am J Physiol Renal Physiol. 2004 Feb;286(2):F323-30. Epub 2003 Sep 23.

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10495853 Hashimoto S: [The in vivo role of vascular chloride channels in the regulation of glomerular hemodynamics]. Hokkaido Igaku Zasshi. 1999 Sep;74(5):387-94.


The calcium (Ca2+)-dependent chloride channel (CIC) may have a crucial role in the modulation of the effects of Angiotensin II (AII) on vascular smooth muscle cell and glomerular mesangium.
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14679313 Hashimoto S, Kawata T, Schnermann J, Koike T: Chloride channel blockade attenuates the effect of angiotensin II on tubuloglomerular feedback in WKY but not spontaneously hypertensive rats. Kidney Blood Press Res. 2004;27(1):35-42. Epub 2003 Dec 16.


Recent studies have shown that calcium-dependent chloride channels may play a crucial role in the modulation of the vascular effects of angiotensin II (ANG II).
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11353695 Zhang Z, Huang JM, Turner MR, Rhinehart KL, Pallone TL: Role of chloride in constriction of descending vasa recta by angiotensin II. Am J Physiol Regul Integr Comp Physiol. 2001 Jun;280(6):R1878-86.

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