Protein Information

Name IL 10
Synonyms B TCGF; B cell derived T cell growth factor; CSIF; Cytokine synthesis inhibitory factor; IL 10; IL10; IL10A; Interleukin 10…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
14965001 Popova VV, Mel'nichenko SV, Lukashova RG, Man'kovskii BI, Zak KP: [Content of different cytokines in the blood of healthy children and their siblings who are either.positive or negative for diabetes-associated autoantibodies (GADA, 1A-2A, IAA)]. Lik Sprava. 2003 Dec;(8):26-9.

Content of different cytokines (IF alpha, TNF alpha, IL-1 alpha, IL-4, IL-6 and IL-10) was examined in the blood serum in two groups of healthy children-siblings with type 1 diabetes mellitus with and without revealed insulin autoantibodies against pancreatic islets (GADA, IA-2A and IAA) by enzyme-like immunosorbent assay (ELISA).
6(0,0,1,1) Details
15134033 Novota P, Cejkova P, Cerna M, Andel M: [Genetic risk factors in autoimmune diabetes mellitus, their significance and function]. Cas Lek Cesk. 2004;143(3):159-63.


Individual predispositions belong to the genetic polymorphisms in cytokine genes (IL-10, IL-12, IL-18) and the microsatellite polymorphism of MHC class I chain-related gene A (MIC-A).
1(0,0,0,1) Details
17381505 Schloot NC, Hanifi-Moghaddam P, Aabenhus-Andersen N, Alizadeh BZ, Saha MT, Knip M, Devendra D, Wilkin T, Bonifacio E, Roep BO, Kolb H, Mandrup-Poulsen T: Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission. Diabet Med. 2007 May;24(5):512-20. Epub 2007 Mar 22.


Baseline levels were associated with the later clinical course in that low levels of interferon gamma (P = 0.01), IL-10 (P = 0.03) and IL-1R1 (P = 0.009) concentrations were observed in partial remitters.
1(0,0,0,1) Details