Protein Information

Name hTERT
Synonyms ABG deleted variant of telomerase reverse transcriptase; EST 2; EST2; HEST 2; HEST2; TCS 1; TCS1; TERT…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
18097608 Liao ZK, Zhou FX, Luo ZG, Zhang WJ, Xiong J, Bao J, Han G, Zhang MS, Xie CH, Zhou YF: Radio-activation of hTERT promoter in larynx squamous carcinoma cells: an 'indirected-activator' strategy in radio-gene-therapy. Oncol Rep. 2008 Jan;19(1):281-6.

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19173799 Huang CH, Liao ZK, Zhou FX, Wang WF, Xie CH, Zhang HY, Sun WJ, Zhou YF: [hTERT promoter enhances the radiosensitivity to gene-radiation therapy of human laryngeal carcinoma transplanted in nude mice]. Zhonghua Zhong Liu Za Zhi. 2008 Oct;30(10):733-6.

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19375219 Liao Z, Huang C, Zhou F, Xiong J, Bao J, Zhang H, Sun W, Xie C, Zhou Y: Radiation enhances suicide gene therapy in radioresistant laryngeal squamous cell carcinoma via activation of a tumor-specific promoter. Cancer Lett. 2009 Sep 28;283(1):20-8. Epub 2009 Apr 16.


Here, we found that human telomerase reverse transcriptase promoter (hTERTp) had lower activity in laryngeal squamous carcinomas cells than in radioresistant variant cells.
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