Protein Information

Name interleukin 18
Synonyms IFN gamma inducing factor; IGIF; IL 1 gamma; IL 18; IL 1g; IL18; IL1F4; Iboctadekin…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
11317661 Nicoletti F, Conget I, Di Marco R, Speciale AM, Morinigo R, Bendtzen K, Gomis R: Serum levels of the interferon-gamma-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type I diabetes. Diabetologia. 2001 Mar;44(3):309-11.

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16686259 Tso TK, Huang WN, Huang HY, Chang CK: Elevation of plasma interleukin-18 concentration is associated with insulin levels in patients with systemic lupus erythematosus. Lupus. 2006;15(4):207-12.

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15134033 Novota P, Cejkova P, Cerna M, Andel M: [Genetic risk factors in autoimmune diabetes mellitus, their significance and function]. Cas Lek Cesk. 2004;143(3):159-63.


Individual predispositions belong to the genetic polymorphisms in cytokine genes (IL-10, IL-12, IL-18) and the microsatellite polymorphism of MHC class I chain-related gene A (MIC-A).
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