Protein Information

Name superoxide dismutase
Synonyms IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
15139192 Shi M, Cheng R: [Effects of zinc and boron nutrition on balsam pear (Momordica charantia) yield and quality, and polyamines, hormone, and senescence of its leaves]. Ying Yong Sheng Tai Xue Bao. 2004 Jan;15(1):77-80.

The reason was that Zn and B could increase polyamines (PAs), putrescine (Put), spermidine (Spd), spermine (Spm), indole acetic acid (IAA), gibberellic acid (GA3) and ascorbic acid (ASA) contents and superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) activities, and reduce malondialdehyde (MDA), abscisic acid (ABA) contents in leaves, which inhibited membrane lipid peroxidation.
31(0,1,1,1) Details
19390823 Xu X, Zhou Y, Wei S, Ren D, Yang M, Bu H, Kang M, Wang J, Feng J: Molecular cloning and expression of a Cu/Zn-Containing superoxide dismutase from Thellungiella halophila. Mol Cells. 2009 Apr;27(4):423-8. Epub 2009 Apr 13.

2(0,0,0,2) Details
16052681 Huang C, Liu LY, Song TS, Ni L, Yang L, Hu XY, Hu JS, Song LP, Luo Y, Si LS: Apoptosis of pancreatic cancer BXPC-3 cells induced by indole-3-acetic acid in combination with horseradish peroxidase. World J Gastroenterol. 2005 Aug 7;11(29):4519-23.


Level of malondialdehyde (MDA) and activity of superoxide dismutase (SOD) were measured by biochemical methods.
1(0,0,0,1) Details
10489115 Matsuki N, Takanohashi A, Boffi FM, Inanami O, Kuwabara M, Ono K: Hydroxyl radical generation and lipid peroxidation in C2C12 myotube treated with iodoacetate and cyanide. Free Radic Res. 1999 Jul;31(1):1-8.


By the addition of iron-chelating 1 mM deferoxamine to the C2C12 preparation with IAA + CN, both ESR signals of DMPO-OH and DMPO-R were completely abolished, and the release of MDA and LDH were significantly reduced, while cyanide-resistant manganese superoxide dismutase had negligible effects on these parameters.
1(0,0,0,1) Details
19707886 Cunha LT, Pugine SM, Silva MR, Costa EJ, De Melo MP: Microbicidal action of indole-3-acetic acid combined with horseradish peroxidase on Prototheca zopfii from bovine mastitis. Mycopathologia. 2010 Feb;169(2):99-105. Epub 2009 Aug 26.


In addition, P. zopfii antioxidant activity increased measurably in the presence of IAA/HRP (6 h); superoxide dismutase, catalase, glutathione reductase, and glutathione peroxidase increased by 90, 120, 150% and 3.4 times, compared with the controls.
1(0,0,0,1) Details
19107877 Mourao LR, Santana RS, Paulo LM, Pugine SM, Chaible LM, Fukumasu H, Dagli ML, de Melo MP: Protective action of indole-3-acetic acid on induced hepatocarcinoma in mice. Cell Biochem Funct. 2009 Jan;27(1):16-22.


In addition, hepatomorphologic alterations, activity of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR), gene expression of antioxidant enzymes and DNA integrity were evaluated in the liver.
1(0,0,0,1) Details
15019094 de Melo MP, de Lima TM, Pithon-Curi TC, Curi R: The mechanism of indole acetic acid cytotoxicity. Toxicol Lett. 2004 Mar 14;148(1-2):103-11.


Incubation for 24 h in the presence of IAA (1 mM) showed increase in the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase.
1(0,0,0,1) Details
11811534 Reverberi M, Picardo M, Ricelli A, Camera E, Fanelli C, Fabbri AA: Oxidative stress, growth factor production and budding in potato tubers during cold storage. Free Radic Res. 2001 Dec;35(6):833-41.


Cold stress increased both enzymatic antioxidative activities (superoxide dismutase, SOD, E.C.1.15.1.1; catalase, CAT, E.C.1.11.1.6), and alpha-tocopherol levels thus protecting membrane's polyunsaturated lipids.
1(0,0,0,1) Details
12060278 Michaeli R, Philosoph-Hadas S, Riov J, Shahak Y, Ratner K, Meir S: Chilling-induced leaf abscission of Ixora coccinea plants. Physiol Plant. 2001 Nov;113(3):338-345.


The chilling stress under darkness induced a 60% reduction in superoxide dismutase (SOD) activity and significant increases (130-600%) in the activities of several other antioxidative enzymes.
1(0,0,0,1) Details
16277839 Yang L, Song TS, Huang C, Liu LY, Luo Y, Ni L, Si LS: [Mechanism of apoptosis induced by indole-3-acetic acids combined with horseradish peroxidase in leukemia cell line K562]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2005 Oct;13(5):769-73.


To investigate the possible mechanism of apoptosis induced by indole-3-acetic acid (IAA) combined with horseradish peroxidase in leukemia cell line K562, cell proliferation and apoptosis of K562 cell were examined by MTT assay and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL), respectively; the activity of superoxide dismutase (SOD) and the quantitative change of MDA were measured by biochemical method; changes of free radical were determined by 2, 7-dichlorofluorescin diacetate (DCFH-DA) probe with confocal microscopy.
1(0,0,0,1) Details
19329125 Gulmen S, Kiris I, Narin C, Ceylan BG, Mermi B, Sutcu R, Meteoglu I: Tezosentan reduces the renal injury induced by abdominal aortic ischemia-reperfusion in rats. J Surg Res. 2009 Nov;157(1):e7-e13. Epub 2008 Oct 24.


RESULTS: Biochemical analysis showed that aortic IR significantly increased (P < 0.05 versus control) while tezosentan significantly decreased (P < 0.05 versus aortic IR) the tissue levels of malondialdehyde, superoxide dismutase, catalase and myeloperoxidase.
1(0,0,0,1) Details
19436044 Bianco C, Defez R: Medicago truncatula improves salt tolerance when nodulated by an indole-3-acetic acid-overproducing Sinorhizobium meliloti strain. J Exp Bot. 2009;60(11):3097-107. Epub 2009 May 12.


For Mt-RD64 plants higher internal proline contents, almost unchanged hydrogen peroxide levels, and enhanced activity of antioxidant enzymes (superoxide dismutase, total peroxidase, glutathione reductase, and ascorbate peroxidase) were found compared with Mt-1021 plants.
1(0,0,0,1) Details
9792217 Pires de Melo M, Curi TC, Miyasaka CK, Palanch AC, Curi R: Effect of indole acetic acid on oxygen metabolism in cultured rat neutrophil. Gen Pharmacol. 1998 Oct;31(4):573-8.


Indole acetic acid (IAA) stimulates O2.- and H2O2 production in cells with peroxidase activity, such as neutrophils.
0(0,0,0,0) Details