Protein Information

Name catalase
Synonyms CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
18401947 Rout GR, Senapati SK, Panda JJ: Selection of salt tolerant plants of Nicotiana tabacum L. through in vitro and its biochemical characterization. Acta Biol Hung. 2008 Mar;59(1):77-92.


Standard growth parameters such as fresh weight and dry weight of organogenic callus, growth tolerant index and enzyme activity (peroxidase and catalase) were used as indicators of salt tolerance.
1(0,0,0,1) Details
19107877 Mourao LR, Santana RS, Paulo LM, Pugine SM, Chaible LM, Fukumasu H, Dagli ML, de Melo MP: Protective action of indole-3-acetic acid on induced hepatocarcinoma in mice. Cell Biochem Funct. 2009 Jan;27(1):16-22.


In addition, hepatomorphologic alterations, activity of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR), gene expression of antioxidant enzymes and DNA integrity were evaluated in the liver.
1(0,0,0,1) Details
16317662 Oliveira DL, Pugine SM, Ferreira MS, Lins PG, Costa EJ, de Melo MP: Influence of indole acetic acid on antioxidant levels and enzyme activities of glucose metabolism in rat liver. Cell Biochem Funct. 2007 Mar-Apr;25(2):195-201.


Treatments with 18 mg and 40 mg IAA decreased the activity of catalase by both subcutaneous (30% and 26%) or gavage administration (19% and 28%), respectively.
1(0,0,0,1) Details
11811534 Reverberi M, Picardo M, Ricelli A, Camera E, Fanelli C, Fabbri AA: Oxidative stress, growth factor production and budding in potato tubers during cold storage. Free Radic Res. 2001 Dec;35(6):833-41.


Cold stress increased both enzymatic antioxidative activities (superoxide dismutase, SOD, E.C.1.15.1.1; catalase, CAT, E.C.1.11.1.6), and alpha-tocopherol levels thus protecting membrane's polyunsaturated lipids.
1(0,0,0,1) Details
16120449 Lins PG, Valle CR, Pugine SM, Oliveira DL, Ferreira MS, Costa EJ, De Melo MP: Effect of indole acetic acid administration on the neutrophil functions and oxidative stress from neutrophil, mesenteric lymph node and liver. Life Sci. 2006 Jan 2;78(6):564-70. Epub 2005 Aug 24.


But in the liver, the treatments imposed a significant decrease in the activity of catalase of 19% and 30% for T2 and T3, respectively, in comparison with the control.
1(0,0,0,1) Details
15139192 Shi M, Cheng R: [Effects of zinc and boron nutrition on balsam pear (Momordica charantia) yield and quality, and polyamines, hormone, and senescence of its leaves]. Ying Yong Sheng Tai Xue Bao. 2004 Jan;15(1):77-80.

The reason was that Zn and B could increase polyamines (PAs), putrescine (Put), spermidine (Spd), spermine (Spm), indole acetic acid (IAA), gibberellic acid (GA3) and ascorbic acid (ASA) contents and superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) activities, and reduce malondialdehyde (MDA), abscisic acid (ABA) contents in leaves, which inhibited membrane lipid peroxidation.
31(0,1,1,1) Details
17029711 Gazarian IG, Lagrimini LM: Anaerobic stopped-flow studies of indole-3-acetic acid oxidation by dioxygen catalysed by horseradish C and anionic tobacco peroxidase at neutral pH: catalase effect. Biophys Chem. 1998 Jun 9;72(3):231-7.

4(0,0,0,4) Details
16460736 Kim DS, Jeon SE, Jeong YM, Kim SY, Kwon SB, Park KC: Hydrogen peroxide is a mediator of indole-3-acetic acid/horseradish peroxidase-induced apoptosis. FEBS Lett. 2006 Feb 20;580(5):1439-46. Epub 2006 Jan 31.


Furthermore, catalase was found to prevent IAA/HRP-induced apoptotic cell death, indicating that IAA/HRP-produced hydrogen peroxide (H2O2) may be involved in the apoptotic process.
3(0,0,0,3) Details
9639583 Gazarian IG, Lagrimini LM, Mellon FA, Naldrett MJ, Ashby GA, Thorneley RN: Identification of skatolyl hydroperoxide and its role in the peroxidase-catalysed oxidation of indol-3-yl acetic acid. Biochem J. 1998 Jul 1;333 ( Pt 1):223-32.


Skatolyl hydroperoxide is degradable by catalase.
2(0,0,0,2) Details
16880616 Kim DS, Kim SY, Jeong YM, Jeon SE, Kim MK, Kwon SB, Park KC: Indole-3-acetic acid/horseradish peroxidase-induced apoptosis involves cell surface CD95 (Fas/APO-1) expression. Biol Pharm Bull. 2006 Aug;29(8):1625-9.


We also found that IAA/HRP increases cell surface CD95 (Fas/APO-1) expression, and that this is blocked by catalase treatment.
2(0,0,0,2) Details
16129608 Tang W, Newton RJ: Peroxidase and catalase activities are involved in direct adventitious shoot formation induced by thidiazuron in eastern white pine (Pinus strobus L.) zygotic embryos. Plant Physiol Biochem. 2005 Aug;43(8):760-9. Epub 2005 Jun 13.

2(0,0,0,2) Details
18020698 Lopez ML, Peralta-Videa JR, Castillo-Michel H, Martinez-Martinez A, Duarte-Gardea M, Gardea-Torresdey JL: Lead toxicity in alfalfa plants exposed to phytohormones and ethylenediaminetetraacetic acid monitored by peroxidase, catalase, and amylase activities. Environ Toxicol Chem. 2007 Dec;26(12):2717-23.

2(0,0,0,2) Details
19367647 Cardenas-Rodriguez N, Guzman-Beltran S, Medina-Campos ON, Orozco-Ibarra M, Massieu L, Pedraza-Chaverri J: The effect of nordihydroguaiaretic acid on iodoacetate-induced toxicity in cultured neurons. J Biochem Mol Toxicol. 2009 Mar;23(2):137-42.


We found that IAA caused a dose-dependent decrease in cell viability of cultured neurons with an IC (50) of 18.4 microM and induced increased activity of catalase, glutathione peroxidase, and glutathione-S-transferase.
1(0,0,0,1) Details
19885021 Lee SJ, Kwon CH, Kim YK: Alterations in membrane transport function and cell viability induced by ATP depletion in primary cultured rabbit renal proximal tubular cells. Korean J Physiol Pharmacol. 2009 Feb;13(1):15-22. Epub 2009 Feb 28.


Alterations in Na (+)-dependent phosphate uptake and cell viability induced by ATP depletion were prevented by the hydrogen peroxide scavenger such as catalase and the hydroxyl radical scavengers (dimethylthiourea and thiourea), and amino acids (glycine and alanine).
1(0,0,0,1) Details
19707886 Cunha LT, Pugine SM, Silva MR, Costa EJ, De Melo MP: Microbicidal action of indole-3-acetic acid combined with horseradish peroxidase on Prototheca zopfii from bovine mastitis. Mycopathologia. 2010 Feb;169(2):99-105. Epub 2009 Aug 26.


In addition, P. zopfii antioxidant activity increased measurably in the presence of IAA/HRP (6 h); superoxide dismutase, catalase, glutathione reductase, and glutathione peroxidase increased by 90, 120, 150% and 3.4 times, compared with the controls.
1(0,0,0,1) Details
15019094 de Melo MP, de Lima TM, Pithon-Curi TC, Curi R: The mechanism of indole acetic acid cytotoxicity. Toxicol Lett. 2004 Mar 14;148(1-2):103-11.


Incubation for 24 h in the presence of IAA (1 mM) showed increase in the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase.
1(0,0,0,1) Details
17286561 Yu T, Zheng XD: Indole-3-acetic acid enhances the biocontrol of Penicillium expansum and Botrytis cinerea on pear fruit by Cryptococcus laurentii. FEMS Yeast Res. 2007 May;7(3):459-64. Epub 2007 Feb 5.


This study evaluated the efficacy of indole-3-acetic acid (IAA) alone or with a biocontrol yeast, Cryptococcus laurentii, in the inhibition of blue and gray mold diseases (Penicillium expansum and Botrytis cinerea) on pear fruit.
0(0,0,0,0) Details
19329125 Gulmen S, Kiris I, Narin C, Ceylan BG, Mermi B, Sutcu R, Meteoglu I: Tezosentan reduces the renal injury induced by abdominal aortic ischemia-reperfusion in rats. J Surg Res. 2009 Nov;157(1):e7-e13. Epub 2008 Oct 24.


RESULTS: Biochemical analysis showed that aortic IR significantly increased (P < 0.05 versus control) while tezosentan significantly decreased (P < 0.05 versus aortic IR) the tissue levels of malondialdehyde, superoxide dismutase, catalase and myeloperoxidase.
1(0,0,0,1) Details
9792217 Pires de Melo M, Curi TC, Miyasaka CK, Palanch AC, Curi R: Effect of indole acetic acid on oxygen metabolism in cultured rat neutrophil. Gen Pharmacol. 1998 Oct;31(4):573-8.


Indole acetic acid (IAA) stimulates O2.- and H2O2 production in cells with peroxidase activity, such as neutrophils.
0(0,0,0,0) Details