Name | activator protein 1 |
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Synonyms | AP1; Activator protein 1; JUN; Proto oncogene c jun; Protooncogene c jun; Transcription factor AP 1; V jun avian sarcoma virus 17 oncogene homolog; c Jun… |
Name | IAA |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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19655312 | Van Cleemput M, Heyerick A, Libert C, Swerts K, Philippe J, De Keukeleire D, Haegeman G, De Bosscher K: Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma. Mol Nutr Food Res. 2009 Sep;53(9):1143-55. All three studied classes of HBA blocked the tumor necrosis factor alpha (TNF)-induced production of the cytokine IL6, and inhibited the transactivation of the pro-inflammatory transcription factors nuclear factor kappa B (NF-kappaB), activator protein-1 (AP-1), and cAMP-response element-binding protein (CREB). |
1(0,0,0,1) | Details |
9563654 | Bae SK, Baek JH, Lee YM, Lee OH, Kim KW: Hypoxia-induced apoptosis in human hepatocellular carcinoma cells: a possible involvement of the 6-TG-sensitive protein kinase (s)-dependent signaling pathway. Cancer Lett. 1998 Apr 10;126(1):97-104. Hypoxia-induced apoptosis was associated with a marked induction of c-jun and c-fos messenger RNAs. |
3(0,0,0,3) | Details |
15051816 | Gietzen DW, Ross CM, Hao S, Sharp JW: Phosphorylation of eIF2alpha is involved in the signaling of indispensable amino acid deficiency in the anterior piriform cortex of the brain in rats. J Nutr. 2004 Apr;134(4):717-23. In cells intensely labeled for cytoplasmic p-eIF2alpha, there was intense fluorescence for c-Jun in the nucleus. |
1(0,0,0,1) | Details |