Protein Information

Name annexin V
Synonyms ANX 5; PP4; ENX2; ANX5; ANXA 5; ANXA5; Anchorin CII; Annexin 5…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
15482374 d'Anglemont de Tassigny A, Souktani R, Henry P, Ghaleh B, Berdeaux A: Volume-sensitive chloride channels (ICl,vol) mediate doxorubicin-induced apoptosis through apoptotic volume decrease in cardiomyocytes. Fundam Clin Pharmacol. 2004 Oct;18(5):531-8.


AVD as well as increases in the early markers of apoptosis, annexin V labeling and caspase-3 activity.
1(0,0,0,1) Details
18164246 d'Anglemont de Tassigny A, Berdeaux A, Souktani R, Henry P, Ghaleh B: The volume-sensitive chloride channel inhibitors prevent both contractile dysfunction and apoptosis induced by doxorubicin through PI3kinase, Akt and Erk 1/2. Eur J Heart Fail. 2008 Jan;10(1):39-46.


Doxorubicin induced increases in both annexin V labelling and caspase-3 activity and decreases in cell volume.
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15716615 Choi SJ, Kim MH, Lim SW, Gwak MS: Effect of ketamine on apoptosis by energy deprivation in astroglioma cells using flow cytometry system. J Korean Med Sci. 2005 Feb;20(1):113-20.


FITC-annexin-V staining and propidium iodide binding were determined by using flow cytometry.
1(0,0,0,1) Details
12244574 Greco O, Dachs GU, Tozer GM, Kanthou C: Mechanisms of cytotoxicity induced by horseradish peroxidase/indole-3-acetic acid gene therapy. J Cell Biochem. 2002;87(2):221-32.

In the present work, some of the molecular and morphological features of the cells treated with HRP/IAA gene therapy were analysed.
Human T24 bladder carcinoma cells transiently transfected with the HRP cDNA and exposed to the prodrug IAA showed chromatin condensation, formation of apoptotic bodies, DNA fragmentation, and Annexin V binding.
1(0,0,0,1) Details