Protein Information

Name NPH4
Synonyms NPH 4; NPH4; NXPH 4; NXPH4; Neurexophilin 4; Neurexophilin 4 precursor; UNQ1928/PRO4403; Neurexophilin 4s…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
14973283 Hardtke CS, Ckurshumova W, Vidaurre DP, Singh SA, Stamatiou G, Tiwari SB, Hagen G, Guilfoyle TJ, Berleth T: Overlapping and non-redundant functions of the Arabidopsis auxin response factors MONOPTEROS and NONPHOTOTROPIC HYPOCOTYL 4. Development. 2004 Mar;131(5):1089-100.

Here, interaction assays, expression studies and combinations of multiple loss- and gain-of-function mutants were used to assess the roles of two ARFs, NONPHOTOTROPIC HYPOCOTYL 4 (NPH4/ARF7) and MONOPTEROS (MP/ARF5), in Arabidopsis development.
Finally, we demonstrate antagonistic interaction between ARF and Aux/IAA gene functions in Arabidopsis development.
4(0,0,0,4) Details
16854942 Muto H, Nagao I, Demura T, Fukuda H, Kinjo M, Yamamoto KT: Fluorescence cross-correlation analyses of the molecular interaction between an Aux/IAA protein, MSG2/IAA19, and protein-protein interaction domains of auxin response factors of arabidopsis expressed in HeLa cells. Plant Cell Physiol. 2006 Aug;47(8):1095-101. Epub 2006 Jul 18.


We transiently expressed the C-terminal protein-protein interaction domains (CTDs) of Arabidopsis ARFs, MP/ARF5 and NPH4/ARF7, and MSG2/IAA19, fused to fluorescent proteins in HeLa cells, and determined their molecular interactions with fluorescence cross-correlation spectroscopy (FCCS).
2(0,0,0,2) Details
16176952 Ellis CM, Nagpal P, Young JC, Hagen G, Guilfoyle TJ, Reed JW: AUXIN RESPONSE FACTOR1 and AUXIN RESPONSE FACTOR2 regulate senescence and floral organ abscission in Arabidopsis thaliana. Development. 2005 Oct;132(20):4563-74. Epub 2005 Sep 21.


Two other ARF genes, NPH4/ARF7 and ARF19, were also induced by senescence, and mutations in these genes enhanced arf2 phenotypes.
2(0,0,0,2) Details
19704497 Sato A, Yamamoto KT: What's the physiological role of domain II-less Aux/IAA proteins? . Plant Signal Behav. 2008 Jul;3(7):496-7.


Because IAA20 and IAA30 were early auxin-inducible and were expressed in the root apical meristem, they may have a physiological role in maintaining the stem cell niche of root, by keeping the activity of MP/ARF5 and NPH4/ARF7 at an acceptable level.
1(0,0,0,1) Details