Protein Information

Name IFNgamma
Synonyms IFG; IFI; IFN gamma; IFNG; IFNgamma; Immune interferon; Interferon gamma; Interferon gamma precursor…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
19446535 Kjaer K, Strobaek D, Christophersen P, Ronn LC: Chloride channel blockers inhibit iNOS expression and NO production in IFNgamma-stimulated microglial BV2 cells. Brain Res. 2009 Jul 24;1281:15-24. Epub 2009 May 13.


Here we investigate the effects of established chloride channel blockers with different chemical structures on interferon-gamma (IFNgamma)-induced activation of the murine microglial cell line, BV2.
2(0,0,0,2) Details
11317661 Nicoletti F, Conget I, Di Marco R, Speciale AM, Morinigo R, Bendtzen K, Gomis R: Serum levels of the interferon-gamma-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type I diabetes. Diabetologia. 2001 Mar;44(3):309-11.

2(0,0,0,2) Details
16686259 Tso TK, Huang WN, Huang HY, Chang CK: Elevation of plasma interleukin-18 concentration is associated with insulin levels in patients with systemic lupus erythematosus. Lupus. 2006;15(4):207-12.


IL-12 has a synergistic effect with IL-18, and both cytokines are inducers of interferon (IFN)-gamma.
1(0,0,0,1) Details
18241652 Li RJ, Qiu SD, Chen HX, Wang LR: [Immunomodulatory effects of Astragalus polysaccharide in diabetic mice] . Zhong Xi Yi Jie He Xue Bao. 2008 Feb;6(2):166-70.


The levels of cytokine interferon-gamma (IFN-gamma) and interleukin-4 (IL-4) secreted by splenocytes were determined by enzyme linked immunosorbent assay (ELISA) method, and the expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in spleens was characterized using Western-blot analysis.
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19458207 Parra M, Yang AL, Lim J, Kolibab K, Derrick S, Cadieux N, Perera LP, Jacobs WR, Brennan M, Morris SL: Development of a murine mycobacterial growth inhibition assay for evaluating vaccines against Mycobacterium tuberculosis. Clin Vaccine Immunol. 2009 Jul;16(7):1025-32. Epub 2009 May 20.


Among the consistently upregulated cytokines detected in the immune cocultures are gamma interferon, growth differentiation factor 15, interleukin-21 (IL-21), IL-27, and tumor necrosis factor alpha.
1(0,0,0,1) Details
17381505 Schloot NC, Hanifi-Moghaddam P, Aabenhus-Andersen N, Alizadeh BZ, Saha MT, Knip M, Devendra D, Wilkin T, Bonifacio E, Roep BO, Kolb H, Mandrup-Poulsen T: Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission. Diabet Med. 2007 May;24(5):512-20. Epub 2007 Mar 22.


Baseline levels were associated with the later clinical course in that low levels of interferon gamma (P = 0.01), IL-10 (P = 0.03) and IL-1R1 (P = 0.009) concentrations were observed in partial remitters.
1(0,0,0,1) Details