| Name | adenosine A1 receptors |
|---|---|
| Synonyms | A1AR; ADORA 1; ADORA1; Adenosine A1 receptor; RDC 7; RDC7; Adenosine A1 receptors |
| Name | IAA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15619546 | Rogel A, Bromberg Y, Sperling O, Zoref-Shani E: Phospholipase C is involved in the -activated signal transduction pathway conferring protection against iodoacetic acid-induced injury in primary rat neuronal cultures. Neurosci Lett. 2005 Jan 20;373(3):218-21. Epub 2004 Oct 30. The cultured neurons could be protected against the insult by activation of the adenosine A1 receptors and by presence of antioxidants. |
2(0,0,0,2) | Details |
| 10660114 | Sinclair CJ, Shepel PN, Geiger JD, Parkinson FE: Stimulation of nucleoside efflux and inhibition of adenosine kinase by A1 receptor activation. Biochem Pharmacol. 2000 Mar 1;59(5):477-83. The adenosine A1 receptor selective agonist N6-cyclohexyladenosine (CHA, 300 nM) increased the release of [3H] nucleoside induced by IAA treatment by 39% (P < 0.05). |
2(0,0,0,2) | Details |
| 17065107 | Rogel A, Bromberg Y, Sperling O, Zoref-Shani E: The neuroprotective -activated signal transduction pathway involves activation of phospholipase C. Nucleosides Nucleotides Nucleic Acids. 2006;25(9-11):1283-6. We have demonstrated before that exposure of neuronal cultures to poisoning by iodoacetic acid (IAA) followed by "reperfusion" (IAA-R insult), results in severe cytotoxicity, which could be markedly attenuated by prior activation of the adenosine A1 receptors. |
1(0,0,0,1) | Details |