Protein Information

Name CYP2E1
Synonyms CPE 1; Flavoprotein linked monooxygenase; Xenobiotic monooxygenase; Microsomal monooxygenase; CPE1; CYP2E; CYP2E1; CYP2E1 protein…

Compound Information

Name IBA
CAS

Reference List

PubMed Abstract RScore(About this table)
11201664 Iba MM, Fung J, Gonzalez FJ: Functional Cyp2e1 is required for substantial in vivo formation of 2,5-hexanedione from n-hexane in the mouse. Arch Toxicol. 2000 Dec;74(10):582-6.

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12147272 Iba MM, Nguyen T, Fung J: CYP1A1 induction by pyridine and its metabolites in HepG2 cells. Arch Biochem Biophys. 2002 Aug 15;404(2):326-34.


Pyridine elevated CYP1A1 mRNA abundance 4.6-fold in HepG2 cells transfected with a human CYP2E1 expression vector relative to the abundance of the transcript in empty vector-transfected (control) HepG2 cells; the elevation was inhibited by the CYP2E1 inhibitor dimethyl sulfoxide.
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8287374 Iba MM, Bennett S, Storch A, Ghosal A, Thomas PE: Synergistic induction of rat microsomal CYP1A1 and CYP1A2 by acetone in combination with pyridine. Cancer Lett. 1993 Oct 15;74(1-2):69-74.


The effect of exposure to acetone, pyridine or acetone in combination with pyridine on microsomal CYP1A1, CYP1A2 and CYP2E1 levels and their catalytic activities was determined in the rat.
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