| Name | beta adrenergic receptors (protein family or complex) |
|---|---|
| Synonyms | Beta adrenoceptor; Beta adrenoceptor; Beta adrenergic receptor; Beta adrenergic receptors; Beta adrenoceptor; Beta adrenoceptors; Beta adrenoceptors |
| Name | IBA |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9699248 | Inomata H, Mimata T, Wakui M: Isoprenaline enhances both voltage-dependent Ba2+ and K+ currents in guinea-pig vas deferens. Tohoku J Exp Med. 1998 Apr;184(4):317-20. This ISO-induced enhancement of IBa seems to be contradictory to the suppression of contraction by beta-adrenoceptor activation in normal Krebs solution. |
112(1,2,2,2) | Details |
| 11179395 | Zhong J, Hume JR, Keef KD: beta-Adrenergic receptor stimulation of L-type Ca2+ channels in rabbit portal vein myocytes involves both alphas and betagamma G protein subunits. J Physiol. 2001 Feb 15;531(Pt 1):105-15. Peak Ba2+ current (IBa) in freshly isolated rabbit portal vein smooth muscle cells was significantly increased by bath application of 0.5 microM isoproterenol (isoprenaline; ISO) when measured using the whole-cell patch clamp method (53 +/- 3 % increase, n = 15). |
3(0,0,0,3) | Details |
| 9479031 | Sako H, Sperelakis N, Yatani A: Ca2+ entry through cardiac L-type Ca2+ channels modulates beta-adrenergic stimulation in mouse ventricular myocytes. Pflugers Arch. 1998 Apr;435(5):749-52. beta-adrenergic receptor (beta-AR) stimulation increases cardiac L-type Ca2+ channel (CaCh) currents via cAMP-dependent phosphorylation. We report here that the affinity and maximum response of CaCh to isoproterenol (Iso), in mouse ventricular myocytes were significantly higher when Ba2+ was used as the charge carrier (IBa) instead of Ca2+ (ICa). |
1(0,0,0,1) | Details |
| 8718981 | Aggarwal R, Boyden PA: Altered pharmacologic responsiveness of reduced L-type currents in myocytes surviving in the infarcted heart. J Cardiovasc Electrophysiol. 1996 Jan;7(1):20-35. Furthermore, application of forskolin (1 micro M and 10 micro M) or intracellular cAMP (200 micro M), agents known to act downstream of the beta-receptor, also produced a smaller increase in peak IBa density in IZs versus NZs, suggesting that multiple defects exist in the beta-adrenergic signaling pathway of IZs. The pharmacologic responses of macroscopic L-type calcium channel currents to the dihydropyridine agonist, Bay K 8644, and beta-adrenergic receptor stimulation by isoproterenol were studied in myocytes enzymatically dissociated from the epicardial border zone of the arrhythmic 5-day infarcted canine heart (IZs). |
1(0,0,0,1) | Details |
| 9038813 | Huerta M, Trujillo X, Vasquez C: beta-Adrenergic modulation of Ba2+ currents and K+ contractures in frog slow skeletal muscle fibers. Am J Physiol. 1997 Jan;272(1 Pt 1):C77-81. beta-Adrenergic modulation of the Ba2+ current (IBa) and K+ contracture in slow skeletal muscle fibers of the frog (Rana pipiens) were investigated in intact fibers with the three-microelectrode voltage-clamp technique and isometric tension measurements. Thus the effect was mediated mainly by beta-adrenergic receptors. |
1(0,0,0,1) | Details |
| 9300300 | Mitcheson JS, Hancox JC, Levi AJ: Cultured adult rabbit myocytes: effect of adding supplements to the medium, and response to isoprenaline. J Cardiovasc Electrophysiol. 1997 Sep;8(9):1020-30. CONCLUSIONS: Supplemented medium improved IBa,L density in cultured myocytes. beta-Adrenergic receptors and intracellular messenger pathways appear to remain intact in adult rabbit myocytes cultured for up to 4 days. |
1(0,0,0,1) | Details |
| 9950862 | Liu W, Yasui K, Arai A, Kamiya K, Cheng J, Kodama I, Toyama J: beta-adrenergic modulation of L-type Ca2+-channel currents in early-stage embryonic mouse heart. Am J Physiol. 1999 Feb;276(2 Pt 2):H608-13. These results indicate that the L-type Ca2+-channel currents are modulated by beta-adrenergic receptors in the embryonic mouse heart as early as 9.5 dpc, probably via a cAMP-dependent pathway. In whole cell voltage-clamp experiments, the Ca2+-channel currents were measured as Ba2+ currents (IBa). |
1(0,0,0,1) | Details |
| 8713732 | Masuda H, Sumii K, Sperelakis N: Developmental changes in beta-adrenergic and muscarinic modulations of Ca2+ currents in fetal and neonatal ventricular cardiomyocytes of the rat. Reprod Fertil Dev. 1996;8(1):129-35. These findings are consistent with the steep increase in number of beta-adrenergic receptors that occurs between fetal days 18 and 20 (Kojima, Sperelakis & Sada, 1990a: Kojima, Ishima, Taniguchi, Kimura, Sada & Sperelakis, 1990C). Developmental changes of the beta-adrenergic and muscarinic modulations acting on the slow Ca2+ channels in rat ventricular cardiomyocytes were investigated using Ba2+ as the charge carrier (IBa (L)). |
1(0,0,0,1) | Details |
| 8772132 | Tiaho F, Nerbonne JM: VIP and secretin augment cardiac L-type calcium channel currents in isolated adult rat ventricular myocytes. Pflugers Arch. 1996 Sep;432(5):821-30. Using the whole-cell patch-clamp technique, we show here that VIP enhances Ca2+ and Ba2+ currents (IBa) through voltage-dependent L-type Ca2+ channels in adult rat ventricular myocytes. |
0(0,0,0,0) | Details |
| 9374768 | Zhong J, Hwang TC, Adams HR, Rubin LJ: Reduced L-type current in ventricular myocytes from endotoxemic guinea pigs. Am J Physiol. 1997 Nov;273(5 Pt 2):H2312-24. Correspondingly, endotoxemic myocytes demonstrated significantly reduced peak ICa,L density (3.5 +/- 0.2 pA/pF) and Ba2+ current (IBa) density (7.3 +/- 0.5 pA/pF) compared with respective values of control myocytes (ICa,L) density 6.1 +/- 0.3 pA/pF, IBa density 11.3 +/- 0.8 pA/pF; P < 0.05). |
0(0,0,0,0) | Details |