Protein Information

Name cytochrome c
Synonyms CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs

Compound Information

Name deltamethrin
CAS

Reference List

PubMed Abstract RScore(About this table)
18724894 Guo L, Sun M, Xu PP, Xu YP, Lu HP, Si HY, Yan H: [Effects of melatonin on nerve cell apoptosis and expression of Bcl-2 & cytochrome C genes in rat cerebrum with deltamethrin induction]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2008 Apr;26(4):215-8.

CONCLUSION: MT can protect nerve cell against deltamethrin induced brain injury by inhibiting nerve cell apoptosis, downregulate the protein expression of cytochrome C gene and upregulate the protein expression of bcl-2 gene.
95(1,1,3,5) Details
17304643 Chen D, Huang X, Liu L, Shi N: Deltamethrin induces mitochondrial membrane permeability and altered expression of cytochrome C in rat brain. J Appl Toxicol. 2007 Jul-Aug;27(4):368-72.

The results of the study demonstrated that deltamethrin induced a decreased mitochondrial membrane potential and increased permeability, and reduced the expression of cytochrome c, thus depressing the activity of cytochrome c oxidase significantly.
94(1,1,3,4) Details
16824334 Chen D, Shi N, Huang XW, Liu LL: [Effects of deltamethrin on permeability of mitochondrial membrane and expression of cytochrome C in brain tissue of rats]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2006 Jun;24(6):326-9.
19(0,0,3,4) Details
2632242 Catinot R, Hoellinger H, Pfister A, Sonnier M, Simon MT: Effects on rats of subacute intoxication with deltamethrin via an osmotic pump. Drug Chem Toxicol. 1989 Sep-Dec;12(3-4):173-96.

Succinate cytochrome c reductase, citrate synthase and cytochrome c oxidase were essayed, only this last showed a significant enhancement in deltamethrin treated rats.
7(0,0,1,2) Details
20235118 Sarapusit S, Pethuan S, Rongnoparut P: Mosquito NADPH-cytochrome P450 oxidoreductase: kinetics and role of phenylalanine amino acid substitutions at leu86 and leu219 in CYP6AA3-mediated deltamethrin metabolism. Arch Insect Biochem Physiol. 2010 Apr;73(4):232-44.

When supplemented with exogenous flavin cofactors, the activity of flAnCYPOR-mediated cytochrome c reduction was increased.
2(0,0,0,2) Details
17598560 Kaewpa D, Boonsuepsakul S, Rongnoparut P: Functional expression of mosquito NADPH-cytochrome P450 reductase in Escherichia coli. J Econ Entomol. 2007 Jun;100(3):946-53.

The membrane-bound form containing N-terminal membrane anchor was subjected to purification, and K, values were determined for NADPH and cytochrome c.
Initial test suggested that CYP6AA3 could play a role in deltamethrin metabolism.
1(0,0,0,1) Details