| Name | glucagon |
|---|---|
| Synonyms | GCG; GLP 1; GLP1; GLP 2; GLP2; GRPP; Glicentin related polypeptide; Glucagon… |
| Name | deltamethrin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10995774 | Hoy M, Bokvist K, Xiao-Gang W, Hansen J, Juhl K, Berggren PO, Buschard K, Gromada J: Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells. J Biol Chem. 2001 Jan 12;276(2):924-30. Phentolamine reduced glucagon release (IC (50) = 1.2 microm) from intact islets by 40%, an effect abolished by pertussis toxin, cyclosporin A, and deltamethrin. |
34(0,1,1,4) | Details |
| 11533141 | Gromada J, Hoy M, Buschard K, Salehi A, Rorsman P: Somatostatin inhibits exocytosis in rat pancreatic alpha-cells by G (i2)-dependent activation of calcineurin and depriming of secretory granules. J Physiol. 2001 Sep 1;535(Pt 2):519-32. The inhibitory effect of somatostatin on exocytosis was mediated by activation of the serine/threonine protein phosphatase calcineurin and was prevented by pretreatment with cyclosporin A and deltamethrin or intracellularly applied calcineurin autoinhibitory peptide. Measurements of cell capacitance were used to investigate the molecular mechanisms by which somatostatin inhibits Ca (2+)-induced exocytosis in single rat glucagon-secreting pancreatic alpha-cells. 2. |
1(0,0,0,1) | Details |
| 16644695 | Ranta F, Avram D, Berchtold S, Dufer M, Drews G, Lang F, Ullrich S: Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4. Diabetes. 2006 May;55(5):1380-90. FK506 (0.1 micromol/l) and another calcineurin inhibitor, deltamethrin (1 micromol/l), attenuated dexamethasone-induced cell death. The stable glucagon-like peptide 1 analog, exendin-4 (10 nmol/l), inhibited dexamethasone-induced apoptosis in mouse beta-cells and INS-1 cells. |
1(0,0,0,1) | Details |